Renal failure Flashcards

1
Q

CKD definition?

A

kidney fxn or damage >= 3 months.

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2
Q

ARF definition?

A

acute loss of renal function occurs during days or weeks.

criteria - 50% increase in Cr, 50% in GFR.

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3
Q

ARF definition?

A

acute loss of renal function occurs during days or weeeks.

criteria - 50% increase in Cr, 50% in GFR.

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4
Q

what is oliguria?

A
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5
Q

what is anuria?

A
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6
Q

Define end stage renal disease?

A

pts receiving dialysis or transplantation. GFR

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7
Q

Stage 1 CKD criteria? management step?

A

nrmal - elevated GFR > 89 mL/min

diagnose combormidities, reduce CVD risk factors

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8
Q

Stage 2 CKD mild criteria? management?

A

GFR 60-89

reduce comorib and CVD risk, estimate progression

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9
Q

Stage 3 CKD moderate Criteria and management?

A

GFR 30-59

evaluate and treat complications

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10
Q

Stage 4 CKD severe criteria and management?

A

15-29 GFR

+ prepare for kidney replacement

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11
Q

Stage 5 CKD criteria, ESRD?

A
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12
Q

Signs of CKD?

A

proteinuria, BUN: CR ratio. GFR changes.

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13
Q

Causes of ESRD?

A

glomuleronephritis, interstitial nephritis, cystic kidney disease. collagen vascular disease.

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14
Q

What is uremic syndrome?

A

constellation of symptoms that occur in severe renal failure?

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15
Q

Defintition and cause of prerenal ARF?

A

intravascular volume depletion. such as fever, vomiting, diarrhea r/t illness. hypoperfusion results.

decrease arterial blood volume, can lead to prerenal azotemia.

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16
Q

definition and cause of intrarenal causes of ARF?

A

tubular, glomuler, interstitial, and vascular injury. can lead to tubular necrosis.

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17
Q

defintition and cause of postrenal ARF?

A

physical obstruction of urine outldow.

could be neoplasm, prostatic enlargement, stridture, etc.

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18
Q

Lab findings of acute glomerulopheritis?

A

BUN:Cr > 20:1

UA - renal casts, RBCs

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19
Q

Etiology of acute glomuleronehprtis?

A

poststreptococcal infction, autoimmune infection

20
Q

labs of interstitial nephritis?

A

BUN: Cr

21
Q

etiology of intersitial nephritis?

A

allergic reaction, drug reaction

22
Q

labs of acute tubular necrosis?

A

BUN: CR

23
Q

ARF definition?

A

acute loss of renal function occurs during days or weeeks.

criteria - 50% increase in Cr, 50% in GFR.

24
Q

what is oliguria?

A
25
Q

diagnostics of CKD? or ARF?

A

BUN, Cr, UA.

can do CT scan or US. or renal biopsy. but not needed.
CT or US looks at extent of damage.

US for postrenal.

biopst looks at glomuerlonephritis.

26
Q

Define end stage renal disease?

A

pts receiving dialysis or transplantation. GFR

27
Q

Stage 1 CKD criteria? management step?

A

nrmal - elevated GFR > 89 mL/min

diagnose combormidities, reduce CVD risk factors

28
Q

Stage 2 CKD mild criteria? management?

A

GFR 60-89

reduce comorib and CVD risk, estimate progression

29
Q

Stage 3 CKD moderate Criteria and management?

A

GFR 30-59

evaluate and treat complications

30
Q

Stage 4 CKD severe criteria and management?

A

15-29 GFR

+ prepare for kidney replacement

31
Q

Stage 5 CKD criteria, ESRD?

A
32
Q

Signs of CKD?

A

proteinuria, BUN: CR ratio. GFR changes.

33
Q

Causes of ESRD?

A

glomuleronephritis, interstitial nephritis, cystic kidney disease. collagen vascular disease.

34
Q

What is uremic syndrome?

A

constellation of symptoms that occur in severe renal failure?

35
Q

Defintition and cause of prerenal ARF?

A

intravascular volume depletion. such as fever, vomiting, diarrhea r/t illness. hypoperfusion results.

decrease arterial blood volume, can lead to prerenal azotemia.

36
Q

definition and cause of intrarenal causes of ARF?

A

tubular, glomuler, interstitial, and vascular injury. can lead to tubular necrosis.

37
Q

defintition and cause of postrenal ARF?

A

physical obstruction of urine outldow.

could be neoplasm, prostatic enlargement, stridture, etc.

38
Q

Lab findings of acute glomerulopheritis?

A

BUN:Cr > 20:1

UA - renal casts, RBCs

39
Q

Etiology of acute glomuleronehprtis?

A

poststreptococcal infction, autoimmune infection

40
Q

labs of interstitial nephritis?

A

BUN: Cr

41
Q

etiology of intersitial nephritis?

A

allergic reaction, drug reaction

42
Q

labs of acute tubular necrosis?

A

BUN: CR

43
Q

etiology of tubular necrosis?

A

hypotension, nephrotxins

44
Q

What are complications of CRF?

A

athersclerosis, CHF ,hypertension, pulmonary edema, pericarditis.

hyperkalemia, metabolic acidosis, hyperparathyroidism, renal osteodystrophies, hyperlipidemia, N/v, depression , insonia, anemia, leukopenia, erytheop deficiency. (particular with ESRD)

45
Q

when is hemodialysis recommended in ARF or CKD?

A

hgb

46
Q

diagnostics of CKD? or ARF?

A

BUN, Cr, UA.

can do CT scan or US. or renal biopsy. but not needed.
CT or US looks at extent of damage.

biopst looks at glomuerlonephritis.

47
Q

TX of CKD or ARF?

A

Ace or ARB for CVD risk reduction. Careful because could worsen renal artery stenosis. Do not use in these patients. watch for hyperkalemia. monitor potassium. if starte check labs 1 week after intiation.

control lipids!
limit intake of K. salt, and reduce phosphorous.
require supplemental calcium.