glomerulonephritis

Question 1

glomerulonephritis definition?

Answer 1

inflammation of glomeruli in kidneys.

Question 2

what is the function of the glomeruli?

Answer 2

to remove waste and excess electrolytes and fluid from blood.

Question 3

signs of glomerulonephritis include ?

Answer 3

pink or cola colored urine. hematuria, foamy urine w/proteinuria. hypertension, edema of face, hands, feet, abdomen. anemia possible.

Question 4

cause of acute glomerulonephritis?

Answer 4

infection (GABHS, hepatitis, HIV), vasculitis such as pokyarteritis or wegeners granulomatosis.

immune diseases such as lupus, good pastures syndrome, IgA nephropathy.

Question 5

Complications of glomneph?

Answer 5

kidney failure, high blood pressure, blood electrolyte disorders, nephrotic syndrome

Question 6

cause of chronic GN?

Answer 6

unclear. genetics and change in immune system.

Question 7

Diagnostics of GN?

Answer 7

UA and blood analysis - RBC casts, WBC and elevated protein. elevated BUN and CR BUN:CR > 20:1.

CT scan or kidney US can used to evaluate kidney damage.

BIOPST FOR CONFIRMATION OF DIAGNOSIS!

Question 8

tx acute GN?

Answer 8

self limiting. manages underlying cause and protect. antihypertensives, antimicrobrials, systemic corticosteroids and immune suppressants. worsening cases –> plasmpaheresis. dialysis if severe.