Renal Failure Flashcards
Acute renal failure caused from:
- Trauma
- Infection
- Decreased CO
- Dehydration
- Drugs
Acute renal failure S&S
- Anorexia
- Lethargy
- Nausea
- HA
2 types of antibiotics that can cause renal damage
- Aminoglycosides
- Cephalosporins
Aminoglycosides:
Inhibits protein synthesis in Gram (-) bacteria
- Neomycin
- Streptomycin
- Tobrax
- Amican
Cephalosporins
Inhibits synthesis of bacterial cell wall
- Keflex
- Ceclor
- Rocephin
- Maxipime
NSAIDs can cause:
Vasoconstriction that then leads to pre-renal failure
That can lead to interstitial nephritis
If your patient has severe renal disease with oliguria and azotemia, the doctor should order:
Lasix
What is azotemia?
Abnormal high levels of nitrogen in the blood
Avoid heavy metals such as (for renal failure):
- Mercury
- Lead
- Iron
- Industrial pollutants
Always watch which lab result for a patient with renal failure?
-Potassium (K+)
Pre-renal Failure
- Problems affecting the flow of blood before it reaches the kidneys
- Decrease in urinary output due to decreased blood supply to kidney
Renal (Intrarenal) Failure
- Problems with the kidney itself that prevent proper filtration of blood or production of urine
- Decrease in urinary output due to kidney damage to tissues or nephrons
Postrenal Failure
-Problems affecting the movement of urine out of the kidneys
Pre-renal Failure Urinary Output
<400 mL/day
Causes of pre-renal failure
- Dehydration - Hypovolemia (Low BP):
- V/D
- Diuretics
- Blood loss or disruption to the kidneys
- CHF
- Hypoprofusion:
- Low CO
- Cardiac disorders
- Renal artery disease
- Hepatorenal syndrome
Intrarenal Failure Urinary Output
<400 mL/day
Intrarenal (Renal) Failure is also known as:
Acute Tubular Necrosis (ATN)
Causes of Intrarenal (ATN) Failure
- Ischemia
- Nephrotoxic substances (drugs) `
Intrarenal (ATN) Failure causes of ischemia:
- Hemorrhage
- Burns
- Sepsis
- HF
- Transfusion reactions
Intrarenal (ATN) Failure causes of nephrotoxicity:
- Heavy metals
- Medications
- Street drugs
- Contrast dye - x-rays
- Tissue breakdown
3 stages of Acute Tubular Necrosis
- Oliguric
- Polyuric
- Recovery
Oliguric Stage of ATN
- Lasts 10-17 days
- Increased: BUN, Creatinine, K+
- Fluid overload
- CHF
- Peritoneal dialysis
Polyuric Stage of ATN
- Last 2 weeks - 3 months
- Increased: BUN & Creatinine
- Low K+
- Fluid depleted
Recovery Stage of ATN
- Lasts 3 months - 1 year
- Pray the kidney regenerates