Renal Disorders & Diuretic Flashcards
What is an AKI? Which lab tests does it affect?
Acute kidney injury
Abrupt decline in kidney function that is reversible
Elevated creatinine and BUN
What are the three causes of acute renal failure?
- Prerenal : sudden and severe drop in blood pressure or interruption of blood flow to the kidneys from severe injury or illness (affects blood vessels BEFORE the kidneys) — kidneys are not getting blood
- Intrarenal: direct damage to the kidneys by inflammation, toxins, drugs, or infection or reduced blood supply
- Postrenal: sudden obstruction of urine flow due to enlarged prostate, kidney stones, bladder tumor, or injury (obstruction after the kidneys)
What are the possible S&S of an acute kidney disease ?
- fluid volume excess
- metabolic acidosis (volume excess bc can’t be excreted= all waste is acidic so increased fluid that is acidic in body causes metabolic acidosis)
- sodium balance (hyponatremia)
- potassium (hyperkalemia)
- hematological disorder
- calcium deficit and phosphate excess
- waste product accumulation
- neurological disorders
Diseased kidney = hard time excreting the waste
Why is calcium in deficit during an AKD?
Bc the kidneys are needed to activate vitamin D (which is needed to create calcium)
So if kidneys are injured = no activation of vitamin D = less calcium
George biscotti, 58 yrs old, comes to the ER with 10/10 pain to his left flank.
The pain started progressively a few hours prior and got steadily worse.
He took Tylenol and Advil at home 2hrs ago and found no relief.
He has a PMHx of HTN. He also tells you that he had dysuria for the past week and has only been voiding a small amount twice today.
Meds: amlodipine (norvasc) 10mg PO QD
The doctor prescribed:
- Morpine IV 3mg q5min (max dose : 12mg)
- CBC, electrolytes, U/A& C&S
- CT abdo
What do you suspect is going on with mr. biscotti?
A) pyelonephritis
B) rénal calculi
C) UTI
D) AKI
B)
Flank pain indicates the calculi and usually 10/10 pain not relieved by meds is the renal calculi
Not enough data to guess it to be any of the other options
But flank pain = big indicator for renal calculi
What assessments are needed before administering polystyrene sulfonate (kayexelate)?
- make sure pt has no diarrhea (bc won’t attract and absorb k+)
- make sure bowel is working normally or won’t work properly
- assess s&s of hyperkalemia
- blood test to verify k+ levels
- full bowel assessment
- CBC (look at lab values before administering)
Mr. Biscotti scan revealed a 2.5 mm renal calculi which is now resting in the bladder and a UTI.
Iv antibiotic therapy is initiated.
What dietary teaching will you give to this pt?
A) avoid drinking black teas and coffee
B) hydrate with 2-3L daily
C) limit protein intake
D) reduce calcium intake
B) hydration is for the infectious stone struvite as it will help dilute it and help excrete it
Since pt has a UTI it shows it is an infectious stone
A) would be good for the oxalate renal calculi
C) would be good for the yeux acid stone
D) would be a good answer for the calcium stone
What are some risk factors for a urinary calculi?
- concentrated urine
- diet (large amount of calcium, large amount of oxalate and/or proteins)
- low mobility levels
What are some drinks/foods high in oxalate?
Which renal calculi can be caused by this and what the usual therapeutic interventions needed?
Foods/drinks with oxalate:
- coffee
- black tea
- beer
- chocolate
- asparagus
- rhubarb
- spinach
Risk factor for the calcium oxalate renal calculi
Therapeutic interventions:
- increase hydration
- reduce oxalate in diet
What is a struvite urinary calculi? What are its usual therapeutic interventions?
Struvite urinary calculi:
- associated with UTI by bacteria split urea into ammonium in urine
Therapeutic interventions:
- meds
- surgical management
- control infection (antibiotics)
- increased fluids 2-3L / day (to dilute it and help excrete it)
What is the uric acid renal calculi? What usually helps cause it? What is it’s usually therapeutic intervention?
- metabolic produce purines from protein (seafood, meat)
Foods high in purines:
- sardines
- chicken
- pork
- protein powder
Therapeutic intervention:
- reduce urine concentration of uric acid usually with allopurinol
What is a cystine renal calculi? What are its usual therapeutic interventions?
Cystine:
Genetic defect causing absorption of cystine in GI tract and kidneys causing stone formation
Therapeutic intervention:
- hydration and meds
What are some foods that are high in calcium that are a risk factor for the calcium stones?
Dairy
Lentils
Fish
What are the usual elements In nutrition therapy for an AKI?
- fluid and electrolyte restriction (depending on the cause of AKI sometimes increased fluid is ordered)
- increased carbs and fats
- adequate protein intake
- caloric I rate
- potassium restriction
- phosphate restriction
- sodium restriction
- enteral feeds
Will vary depending on type of renal stone and cause
What are meds that should be avoided when having an AKI?
- avoid nephrotoxic drugs (met for min, NSAIDs, cyclosporine, etc..)