GI System And Acid Controlling Meds Flashcards
What are some indications for antacids use?
Acute relief of symptoms of:
- peptic ulcer
- gastritis
- gastric hyperacidity
- reflux
What are some GERD treatment options?
- eat smaller meals
- break time between meals and lying down (2h-3hrs before bedtime)
- no smoking (weakens lower esophagus sphincter)
- control weight (healthy weight to be maintained)
- avoid wearing tight clothes
- relaxation techniques
- medication therapy: antacids, h2 blockers, proton pump inhibitors
What are foods to avoid with GERD?
- should avoid high fat foods
- avoid foods or substances that lower the LES : peppermint
What are some treatment of PUD?
- adéquate rest
- diet modifications : no red and black peppers, no chili pepper, no caffeine, no alcohol, no fried foods
- drug therapy
- smoking cessation
What is the main concept of acid related diseases?
Impairement of the balance Amine the substances secreted by the stomach
What are the 3 classes of acid controlling meds?
- antacids
- H2 antagonist
- PPIs (proton pump inhibitors)
What is an important implementation with antacids related to other meds?
Antacids should never be taken with other meds because it neutralizes the stomach acid immediately.
Other meds are to be avoided for 1-2hrs of taking an antacid
What are the main AE of aluminum and calcium antacids?
Aluminum salts (almagel)
Calcium carbonate (tums)
They can cause constipation due to their constricting effect.
What is often given with aluminum salts (almagel) to prevent AE?
Often given with magnesium to counteract constipation since mg causes diarrhea.
What is a possible AE of magnesium salts (milk of magnesia)?
Can cause diarrhea
What are 3 other AE only caused by calcium carbonate? Other than constipation
What is often given with it to minimize one of those effects?
Calcium carbonate can produce gas and belching
Will often be given with simethicone (ovol) which is an anti gas medication to reduce discomfort
Can also cause kidney stones due to calcium so not recommended for long term use
And rebound hyperacidity
Which antacid is the only one recommended for renal disease (the most easily excreted)?
Aluminium hydroxide salts (Almagel)
What is a big contraindication with magnesium salts (milk of magnesia) or maalox?
Dangerous when used in pts with renal failure bc the failing kidney cannot excrete extra mg which causes accumulation.
Which antacid can cause rebound hyperacidity after medication discontinuation?
Calcium carbonate (tums)
Which conditions would alert for cautious use of antacids?
Caution use Recommended in pts who have HF, HTP, other heart diseases requiring sodium restriction
Especially if antacid is high in sodium content (ex sodium bicarbonate)