Renal Disorders

Question 1

• Post Group A beta hemolytic strep; 10-14d post infx
• Coco-cola colored urine (hematuria), Edema (especially periorbital), HTN, fevers, abd/flank pain, oliguria
• Dx:Biopsy gold standard, UA, SCr, BUN
• Tx: Supportive; Abx

Answer 1

Glomerulonephritis

Question 2

Kidney’s unable to respond to vasopressin (ADH) and therefore levels are high

Answer 2

Nephrogenic Diabetes insipidus

Question 3

Most common cause of acute glomerulonephritis in adults worldwide.

• Often affects young males within days of URI or GI Infx (d/t IgA immune complexes)
• Tx: ACE Inhibitors and steroids

Answer 3

IgA Nephropathy

Question 4

• Small vessel vascultis (thought d/t immune complex deposition; URI often precedes).
• Sx: Purpuric skin lesions on lower extremities (primarily), arthralgia, hematuria indicates renal damage.
• Tx: Steroids

Answer 4

Henoch-Schönlein Purpura

Question 5

• Triad: 1) Thrombocytopenia; 2) Hemolytic anemia; 3) acute renal failure (lysed cells clog glomeruli). Often proceeded by E. coli 0157.
• Tx: usually self limited

Answer 5

Hemolytic uremic syndrome.