Renal Development Flashcards
Urogenital ridge derived from
intermediate mesoderm
nephrogenic cord -> urinary
gonadal/genital ridge -> genitals
Pronephros
kidney in fetus (degenerates)
Pronephric duct
goes to chloaca, remains to become mesonephric duct
Mesonephros
kidney in fetus after pronephros
Mesonephric duct
what does it become
vas + epidiymis + seminal vesicle + ejaculatory duct in males
ureteric bud in males and females
Ureteric bud becomes what part of the nephron
collecting system and after
Blood supply of metanephric kidney
initially from internal iliac
develops blood supply from aorta as it “ascends”
Renal agenesis due to
failure of ureteric bud and metanephric mesoderm (blastema) to contact
Risk factor for renal agenesis
2 vessel cord (only 1 artery)
Multiple renal artery complication
may block ureter
b/c often at inferior pole
due to failure of segmental blood supply to regress
Multicystic dysplastic kidney is due to dilations of what part of the nephron
thin segments
Allantois becomes
urachus
Urogenital sinus portions
vesicle: bladder, continuous w/ allantois
pelvic/middle: bladder neck and prostatic urethra in males, urethra in females
phallic: penile urethra in males
Where urorectal septum fuses w/ tissue in protodeum
perineal body
Trigone is formed from what tissue
mesonephric duct tissue
Problems resulting from a urachus not closing off completely
urachal cyst: cyst formation
urachal sinus: patent on external surface, secretions out umbilicus
urachal fistula: patent on both ends, urine out umbilicus
Extophy of bladder
etiology
association
failure of mesenchymal cells to migrate between ectoderm of abdomen and cloaca
epispadias
Chromaffin cells are derived from
neural crest, produce mostly epi
