Renal Development Flashcards

1
Q

Urogenital ridge derived from

A

intermediate mesoderm
nephrogenic cord -> urinary
gonadal/genital ridge -> genitals

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2
Q

Pronephros

A

kidney in fetus (degenerates)

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3
Q

Pronephric duct

A

goes to chloaca, remains to become mesonephric duct

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4
Q

Mesonephros

A

kidney in fetus after pronephros

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5
Q

Mesonephric duct

what does it become

A

vas + epidiymis + seminal vesicle + ejaculatory duct in males
ureteric bud in males and females

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6
Q

Ureteric bud becomes what part of the nephron

A

collecting system and after

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7
Q

Blood supply of metanephric kidney

A

initially from internal iliac

develops blood supply from aorta as it “ascends”

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8
Q

Renal agenesis due to

A

failure of ureteric bud and metanephric mesoderm (blastema) to contact

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9
Q

Risk factor for renal agenesis

A

2 vessel cord (only 1 artery)

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10
Q

Multiple renal artery complication

A

may block ureter
b/c often at inferior pole
due to failure of segmental blood supply to regress

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11
Q

Multicystic dysplastic kidney is due to dilations of what part of the nephron

A

thin segments

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12
Q

Allantois becomes

A

urachus

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13
Q

Urogenital sinus portions

A

vesicle: bladder, continuous w/ allantois
pelvic/middle: bladder neck and prostatic urethra in males, urethra in females
phallic: penile urethra in males

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14
Q

Where urorectal septum fuses w/ tissue in protodeum

A

perineal body

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15
Q

Trigone is formed from what tissue

A

mesonephric duct tissue

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16
Q

Problems resulting from a urachus not closing off completely

A

urachal cyst: cyst formation
urachal sinus: patent on external surface, secretions out umbilicus
urachal fistula: patent on both ends, urine out umbilicus

17
Q

Extophy of bladder
etiology
association

A

failure of mesenchymal cells to migrate between ectoderm of abdomen and cloaca
epispadias

18
Q

Chromaffin cells are derived from

A

neural crest, produce mostly epi