Normal and Abnormal Reproductive Development Flashcards
SRY gene function
secretes testes-determining factor
forms seminiferous tubules
Production of ovaries requires what
two complete X chromosomes
(47,XXY)
Kleinfelter syndrome
Kleinfelter characteristics
infertility
gynecomastia
impaired sexual function
Turner’s is due to loss of which chromosome
paternal chromosome
True hermaphrodites are what genotype
XX
have one ovary and one testes
Leydig cells
when are they functional
during fetal development
involute after birth
reappear after puberty
Sertoli cells function in development of male
secrete anti-Müllerian hormone
inhibits female duct system development
Oocytes in prophase I until
shortly before ovulation
Oocytes in metaphase II until
fertilization
causes release of 2nd polar body
Paramesonephric duct in males
remnant becomes
prostatic utricle and appendix of testes
Ureteric buds originate from
mesonephric ducts
Paramesonephric ducts fuse to form what
in females
urogenital primordium
Origin of upper 1/3 of vagina
and innervation
paramesonephric ducts
visceral sensory innervation
Origin of lower 2/3 of vagina
and innervation
urogenital sinus
somatic sensory innervation
Mesonephric duct remnant in women
Gartner’s duct or cyst
located outside uterus, may cause pain during intercourse
Müllerian duct agenesis
results in absence of uterus and upper vagina
Common malformation in uterus
septum in middle
can be removed
Ectopic testes
refers to
displacement of testes
not in cryptorchism distribution
Ventral fusion site of lateral penile folds
penile raphae
Urogenital folds become what
in female
labia minora
Labialscrotal swellings become what
in female
labia majora
How does testosterone insensitivity cause female characteristics
lots of estrogen because of testosterone conversion
because of loss of negative feedback
