RENAL BIOPSY Flashcards

1
Q

What are the major clinical uses of kidney biopsy?

A

Diagnosis, therapy selection, prognosis

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2
Q

In which conditions is kidney biopsy useful?

A
  • AKI
  • Nephrotic syndrome
  • Systemic disease
  • Hematuria
  • Transplant allograft
  • CKD
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3
Q

What should be included in the pre-biopsy evaluation?

A
  • History
  • Physical exam
  • Lab tests
  • Review medications
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4
Q

What laboratory data is required for kidney biopsy?

A
  • Biochemical profile
  • CBC
  • Platelet count
  • PT
  • PTT
  • Blood type
  • Urinalysis
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5
Q

What are the contraindications to percutaneous biopsy?

A
  • Uncooperative patient
  • Solitary native kidney
  • Uncontrolled hypertension or bleeding diathesis
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6
Q

What are the non-percutaneous biopsy methods?

A
  • Transvenous biopsy
  • Open biopsy
  • Laparoscopic biopsy
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7
Q

What are the risk factors for bleeding during kidney biopsy?

A
  • Bleeding diathesis
  • Prolonged bleeding time
  • Advanced age
  • Female gender
  • Hypertension
  • Reduced GFR
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8
Q

What is the management protocol for antiplatelet/anticoagulant agents before a biopsy?

A
  • Stop antiplatelet agents 5 days prior
  • Warfarin: INR <1.5
  • Heparin: stop 4-6 hours prior
  • Low-molecular-weight heparin: stop 24 hours prior
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9
Q

Describe the procedure for a percutaneous biopsy.

A
  • Right kidney
  • Real-time ultrasound guidance
  • Local anesthesia
  • Prone position
  • Automated spring-loaded needle
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10
Q

What needle size is recommended for kidney biopsy?

A

16-gauge needle

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11
Q

What are the complications of kidney biopsy?

A
  • Bleeding (most common)
  • Arteriovenous fistula
  • Page Kidney
  • Organ puncture
  • Pneumothorax
  • Infection
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12
Q

What are the post-biopsy care instructions?

A
  • Bedrest
  • Monitor vital signs
  • Repeat labs
  • Observation for 6-24 hours
  • Avoid heavy exercise and blood thinners for 10-14 days
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