RENAL BIOPSY Flashcards
What are the major clinical uses of kidney biopsy?
Diagnosis, therapy selection, prognosis
In which conditions is kidney biopsy useful?
- AKI
- Nephrotic syndrome
- Systemic disease
- Hematuria
- Transplant allograft
- CKD
What should be included in the pre-biopsy evaluation?
- History
- Physical exam
- Lab tests
- Review medications
What laboratory data is required for kidney biopsy?
- Biochemical profile
- CBC
- Platelet count
- PT
- PTT
- Blood type
- Urinalysis
What are the contraindications to percutaneous biopsy?
- Uncooperative patient
- Solitary native kidney
- Uncontrolled hypertension or bleeding diathesis
What are the non-percutaneous biopsy methods?
- Transvenous biopsy
- Open biopsy
- Laparoscopic biopsy
What are the risk factors for bleeding during kidney biopsy?
- Bleeding diathesis
- Prolonged bleeding time
- Advanced age
- Female gender
- Hypertension
- Reduced GFR
What is the management protocol for antiplatelet/anticoagulant agents before a biopsy?
- Stop antiplatelet agents 5 days prior
- Warfarin: INR <1.5
- Heparin: stop 4-6 hours prior
- Low-molecular-weight heparin: stop 24 hours prior
Describe the procedure for a percutaneous biopsy.
- Right kidney
- Real-time ultrasound guidance
- Local anesthesia
- Prone position
- Automated spring-loaded needle
What needle size is recommended for kidney biopsy?
16-gauge needle
What are the complications of kidney biopsy?
- Bleeding (most common)
- Arteriovenous fistula
- Page Kidney
- Organ puncture
- Pneumothorax
- Infection
What are the post-biopsy care instructions?
- Bedrest
- Monitor vital signs
- Repeat labs
- Observation for 6-24 hours
- Avoid heavy exercise and blood thinners for 10-14 days