Renal Flashcards
What’re the 3 stages of renal development?
Pronephros, mesonephros, metanephros
Describe the pronephros
1st part of renal development (week 4), it’s transient and nonfunctional. Develops caudally toward cloaca and disappears leaving the pronephric duct
The mesonephros is found when?
Weeks 4-8
When the mesonephros joins the pronephric duct, what is formed?
The mesonephric duct (aka Wolffian duct, which forms male reproductive organs)
The mesonephic duct opens into the ___.
Cloaca
Around week 5, what forms off of the mesonephric duct?
The ureteric bud (aka metanephric diverticulum)
What develops lateral to the mesonephric duct and gonads?
The paramesonephric ducts (which form female reproductive organs)
What embryolocial structure is associated b/w the clinical findings of an absent vas deferens and ipsilateral regnal agenesis?
Mesonephric duct
When does the metanephros form?
Around week 9; this is the functional kidney
How is the metanephros formed?
By cranial movement of the ureteric bud and it penetrating the metaneprhogenic blastema (aka the nephron)
What structures are derived from the ureteric bud?
Ureter, renal pelvis, calices, collecting tubules (i.e. everything distal to the collecting ducts)
What structures are derived from the metaneprhogenic blastema (nephron)?
Glomerulus, proximal tubule, loop of Henle, distal tubule
Does the kidney ascend or descend during development?
Ascends
What absorbs the ureteric bud caudally?
The genitourinary sinus (i.e. bladder)
At what spinal position does the kidney normally ascend to?
L1/T12; it also rotates in an orientation to that of the psoas muscle
