Renal Flashcards
Patho of glomerulonephritis
Inflammatory reaction in the glomerulus
Antibodies lodge in the glomerulus leading to scarring and decreased filtering
Main cause of glomerulonephritis
Strep
S/S of glomerulonephritis
Sore throat Malaise and HA-retaining toxins Increased BUN and Creatinine Protein and blood in urine (tea/rust colored) Protein leaks out due to holes in glomerulus Flank pain (CVA tenderness) Increased BP Facial edema Decreased UOP Increased urine specific gravity Client will go into fluid volume excess
Treatment of glomerulonephritis
Decreased protein and Na, increased carbs to prevent breaking down protein for energy
Dialysis
How long will blood and protein stay in the urine with glomerulonephritis?
Months
When does diuresis begin after onset of glomerulonephritis?
1-3 weeks
How is fluid replacement determined?
24 hour fluid loss + 500cc = total replacement
Protein makes BUN do what?
Increase
Patho of nephrotic syndrome
Inflammatory response in the glomerulus, big holes form so protein starts leaking in urine, leads to hypoalbuminemia. Without albumin you can’t hold onto fluid in vascular space, so fluid goes into tissues. (edema) Since all fluid is in tissues, blood volume is decreased. Aldosterone is produced to try to replace blood volume, so Na and water are retained, but there is no albumin to hold it, so more fluid goes to tissues.
Total body edema
Anasarca, occurs with nephrotic syndrome
Problems associated with protein loss
Blood clots, protein keeps blood from clotting
Cholesterol and triglycerides are released from the liver compensation by making more albumin, causing an increased release of cholesterol and triglycerides.
Causes of nephrotic syndrome
Bacterial and viral infections NSAIDs Cancer, genetics Systemic dz like lupus/diabetes Strep
S/S of nephrotic syndrome
Proteinuria
Hypoalbuminemia
Edema (anasarca)
Hyperlipidemia
Tx of nephrotic syndrome
Diuretics ACE inhibitors to block aldosterone Prednisone to decrease inflammation and shrink holes in glomerulus-causes immunosuppression Lipid lowering drugs Decrease Na Increase protein-give lasix, could go into fluid excess Dialysis Anticoagulation therapy for 6 months
One kidney dz when you have to have more protein in diet
Nephrotic syndrome
Renal failure requires what?
Bilateral failure
Causes of renal failure
Pre renal
Intra renal
Post renal
Pre renal failure
Blood can’t get to the kidneys
- Hypotension
- Decreased HR, arrhythmias
- Hypovolemia
- Shock
Intra renal failure
Damage has occurred inside kidney
- Glomerulonephritis
- Nephrotic syndrome
- Dyes with heart cath and CT scans
- Drugs (mycins, nephrotoxicity)
- Malignant HTN (uncontrolled)
- DM causes vascular damage
Post renal failure
Urine can’t get out of kidneys
- Enlarged prostate
- Kidney stone
- Tumors
- Ureteral obstruction
- Edematous stoma (ileal conduit)
S/S of renal failure
Increased creatinine and BUN
Anemia
Initially: increased specific gravity
Fixed specific gravity: lose ability to concentrate and dilute urine, fluid challenge: bolus with 250 mL NS
HTN & HF, retaining fluids
Anorexia, n/v, retaining toxins
Itching frost (uremic frost)-take good skin care
Hyperkalemia
Metabolic acidosis
Retain phos leading to decreased serum Ca and Ca is pulled from bones
Why is there anemia with renal failure?
Not enough erythropoietin-stimulates RBC production
Two phases of acute renal failure
Oliguric
Diuretic
Acute renal failure
Kidneys have been damaged by one of the causes: this damage leads to the oliguric phase
Oliguric phase of acute renal failure
Decreased UOP 100-400 mL in 24 hours
Fluid volume excess
Increased K
*Good time do do the fluid challenge
Diuretic phase of acute renal failure
Sudden onset
Increased UOP
Fluid volume deficit
Decreased K
For hemodialysis, the machine does the work of what?
The glomerulus
How often is hemodialysis done
3-4 x per week, so client has to watch what they eat and drink between treatments
What med will clients get during hemodialysis?
An anticoagulant to prevent clots from forming. Usually heparin, so implement bleeding precautions
Do you worry about suicide with hemodialysis pts?
Yes, they depressed. They may use methods like not going to their appointments or eating the wrong diet
Why can’t all clients handle hemodialysis?
Decreased blood volume can lead to chock. Unstable cardiovascular system clients can’t handle it
What meds do you hold before hemodialysis?
Lisinopril (already have decreased BP during)
Nitro
Water soluble vitamins
Antibiotics (won’t do any good if it’s filtered out)
What med CAN you give before hemodialysis?
Famotidine, not filtered by kidneys
Types of vascular access with hemodialysis (must have access)
Arteriovenous fistula
Arteriovenous graft
Both require sx, the site takes weeks to mature and be ready for repeated venipunctures
What rate is blood removed, cleansed, then returned with hemodialysis?
300-800mL/min
What is vascular access?
Site for access to a large blood vessel, very rapid flow is essential for hemodialysis
Arteriovenous fistula
In forearm, anastomosis between an artery and a vein
Arteriovenous graft
Synthetic graft to join artery and vein vessels
How many needles are inserted into the vascular access during hemodialysis?
Two, one allows blood to be pulled form he circulation and set to machine, other is used to retune the filtered blood to client’s circulation
Which end of access removes blood?
Arterial end
Which end of access replaces blood?
Low pressure venous end
Temporary hemodialysis access
The internal jugular or femoral veins are often used for catheter placement. Sx is not required
Care of hemodialysis access
Do not use for IV access to draw blood, admin meds
No BPs, needle sticks, constriction, purse, jewelry
Assessment of hemodialysis access
Ensure potency by palpating for a thrill-cat purring sensation
Auscultate for a bruit-turbulent blood flow
Feel the thrill, hear the bruit
Peritoneal dialysis filter is what
Peritoneal membrane
How to prepare dialysate for peritoneal dialysis
Warm to body temp and infuse into peritoneal cavity by gravity via a tenckhoff catheter
How does the fluid for peritoneal dialysis work
2000-2500 mL fills peritoneal cavity (takes 10 min) and remains for a prescribed amount of time, called the dwell time
Exchange during peritoneal dialysis
After fluid fills peritoneal cavity, the bag is lowered and the fluid, along with he toxins, are drained
Why do we warm the fluid for peritoneal dialysis
Cold promotes vasoconstriction which limits blood flow. We want it warm to vasodilate for more blood flow
What should the drainage look like with peritoneal dialysis?
Clear, straw-colored. Cloudy means infection
Should be able to read a newspaper through the drainage/effluent
What type of clients get peritoneal dialysis?
Someone who can’t tolerate hemodialysis or someone who chooses it
What happens if all the fluid doesn’t come out with peritoneal dialysis?
Reposition
Two types of peritoneal dialysis
Continuous ambulatory
Continuous cycle
Continuous ambulatory peritoneal dialysis
Client has to have energy and a desire to be active
Done 4 x per day, every day
Fluid causes pressure on back, so pt with disc dz or arthritis shouldn’t do this
Clients with colostomy can’t do this, infection risk
Continuous cycle peritoneal dialysis
Connect their peritoneal dialysis cath to a cycler at night and their exchange is done automatically while the sleep. DC in AM. Client has more freedom
Complications of peritoneal dialysis
Peritonitis (cloudy effluent 1st sign) Constant sweet taste Hernia Altered body image Anorexia Low back pain
Dietary needs of the peritoneal client
Increase fiber and protein
They have decreased peristalsis due to abdominal fluid
Big holes in peritoneum and lose protein with each exchange
Continuous renal replace ment therapy
Done in an ICU and is continuous so the client doesn’t have drastic fluid shifts
Never more than 80 mL or blood out of body at once so it doesn’t stress the heart as much
Performed on a client with a fragile cardiovascular status and acute renal failure
S/S of kidney stones/urolithiasis/renal calculi
Pain, N/V
WBC in urine
Hematuria**
Anytime you suspect a kidney stone, do what?
Get a urine specimen ASAP and have it checked for RBS
If a kidney stone is present on specimen, do what?
Give pain meds immediately
Tx for kidney stones
Ketorolac Ondansetron Hydromorphone Increase fluids Maybe need s Strain urine Extracoporeal shock wave lithotripsy