Renal Flashcards
How much blood does the kidney filter?
1600 L/day
What is the functional unit of the kidney?
nephrons
What does the nephron consist of?
glomerulus connected to tubules
What are the three different parts of a tubule?
- proximal convoluted tubule
- loop of henle
- collecting duct
What are the four functions of the kidney?
- filtration
- absorption
- excretion
- secretion
how much glucose and water do the kidneys absorb?
- glucose 100%
- water 85%
What do the kidneys absorb?
- glucose
- amino acids
- water
- sodium
- potassium
- chloride
What do the kidneys excrete?
- wastes
- urea
- excess ketones
The kidneys secrete hormones that control __________________ and _____________
blood pressure, blood components
What do ions that the kidney secrete do?
maintain acid-base balance
What does vasopressin do?
- exerts pressor effect, elevates blood pressure
- increases water reabsorption from distal and collecting tubules
what is renin secreted by and when is secreted?
glomerulus, when blood volume decreases
What does renin do?
stimulate aldosterone to increase sodium absorption and return blood pressure to normal
what is erythropoietin secreted by and what does it do?
kidney, stimulate bone marrow to produce RBC`
What are the S/S of renal disease?
- anemia due to decreased production of EPO
- upset in blood pressure
- decrease activation of vitamin D
- oliguria
- azotemia
When investigating kidney stones …what should a diet history evaluate?
- intake of fluids
- protein (types and amounts)
- calcium
- sodium
- high oxalate foods
- fruits
- veggies
- medications and supplements
What is the % frequency of calcium oxalate or calcium phosphate stones?
70-80%
What is the % frequency of uric acid kidney stones?
10-15%
What is the % frequency of magnesium ammonian phosphate stones?
10-15%
What is the cause of calcium oxalate or calcium phosphate stones?
- low urine volume
- high urinary excretion of Ca
- hyperuricosuria
- hyperoxaluria
- low urine citrate
What is the cause of uric acid kidney stones?
- low urine volume and pH
- metabolic acidosis
- hyperuricosuria
- obesity
- metabolic syndrome
What is the cause of magnesium ammonium phosphate?
-struvite, infection-related (urea-splitting bacteria)
What are the general recommendations for kidney stones?
- at least 3 L fluid/day needed
- adequate calcium intake (1000-1200 mg/day)
- reduce calcium urine load
- reduce sodium intake to 1500 mg/day
- reduce oxalate`
how do you reduce oxalate?
- adequate calcium intake to bind oxalate
- eat fewer high-oxalate foods