Renal Flashcards
GFR:
120-125 ml/min
GFR stands for Glomerular Filtration Rate.
RPF:
660 ml/min
RPF stands for Renal Plasma Flow.
Filtration fraction (FF):
0.2
FF is the fraction of the renal plasma flow that becomes filtrate.
Autoregulation range for renal blood flow:
80-180 mmHg
This range is critical for maintaining stable renal function despite fluctuations in systemic blood pressure.
Renal blood flow (RBF):
1320 ml/min
RBF is the volume of blood delivered to the kidneys per minute.
What percentage of resting cardiac output is RBF?
20-23%
This indicates the significant portion of cardiac output that is allocated to the kidneys.
normalized renal blood flow:
420 ml/min/100g
For comparison: cardiac muscle is 84, skeletal muscle is 2.7, and brain is 54 ml/min/100g.
What is the inulin clearance equal to?
GFR
Inulin is a standard marker for measuring GFR due to its clearance being entirely renal.
Plasma creatinine range:
50-150 μM
Plasma creatinine levels are indicative of kidney function.
Endogenous creatinine clearance:
90-150 ml/min
This clearance is used to estimate GFR in clinical settings.
What does PAH clearance equal?
RPF
PAH (Para-aminohippuric acid) is used to measure renal plasma flow.
Renal threshold of glucose:
10 mM
This is the plasma concentration at which glucose begins to appear in urine.
Normal plasma uric acid range:
150-500 μM
Uric acid levels can be influenced by diet and kidney function.
What is the maximal osmotic concentration in the outer medulla for a short-loop nephron?
600 mosmol/l
This concentration is crucial for urine concentration mechanisms.
What is the maximal osmotic concentration in the inner medulla for a long-loop nephron?
1200 mosmol/l
This higher concentration aids in water reabsorption and urine concentration.
What is the maximum urea concentration in the inner medulla?
600 mM
Urea plays a key role in the kidney’s ability to concentrate urine.
