Regulation of Translation

Question 1

An accumulation of uncharged tRNAs is an indicator of…

a. viral infection

b. osmotic stress

c. amino acid starvation

d. ribosomal arrest

Answer 1

c. amino acid starvation

Question 2

In bacteria, stalled ribosomes are released by _____________ and its partner protein _____________.

Answer 2

tmRNA, small-protein B

Question 3

On the no-go decay pathway, which proteins are Pelota and Hbs1 mimicking?

Answer 3

Eukaryotic release factor 1 (erf1) and Eukaryotic release factor 3 (erf3)

Question 4

A STOP codon should never be found [insert answer] of an exon junction complex

a. upstream
b. downstream

Answer 4

a. upstream

Question 5

“Magic spot” is another name for …? (multiple answers may be correct)

a. Gcn2

b. guanosine pentaphosphate

c. Pelota

d. (p)ppGpp

e. Gcn4

Answer 5

b. guanosine pentaphosphate
and
d. (p)ppGpp

Question 6

What does GEF stand for?

Answer 6

Guanine-nucleotide Exchange Factor