DNA Damage and Direct Repair Flashcards
1
Q
What does inadequate DNA repair lead to?
A
Mutation or cell death
2
Q
Is dsDNA or ssDNA more stable?
A
dsDNA is more stable than ssDNA
3
Q
What can guanine methylation cause?
A
A G-C to A-T transition mutation.
4
Q
What can AGT1 remove alkyl groups from?
A
O6-methylguanine and Sp-methyl phosphotriester
5
Q
Does photolyase use ATP?
A
No, photolyase uses sunlight and FADH cofactor
