Regulation of the Normal Ovarian Menstrual cycle Flashcards

1
Q

length of cycle

A

1st day of vaginal bleeding to the next start of bleeding

usually 25-30

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2
Q

classification of polymenorrheic

A

-cycles <21 days (from start to start is more frequent than 21 days)

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3
Q

Oligomenorrheic

A

cycles prolonged >35 days

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4
Q

Menstrual irregularities are typically at these stages of life

A

extremes of reproductive life. ie. menarche and menopause.

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5
Q

variability of the cycle is seen in the phase

A

follicular

finicky

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6
Q

Oogenesis begins in

A

utero

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7
Q

first half of the cycle this hormone is in charge

A

estrogen

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8
Q

follicular phase comprises what part of the cycle

A
  1. First day of menses until ovulation
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9
Q

____provides the signal for recruitment of a cohort of follicles in the ovary.

A

FSH

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10
Q

With fraternal twins two follicles become dominant..

A

Midfollicular Phase (Selection

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11
Q

Lower basal body temperatures and the development of the follicle occur in this phase

A

follicular

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12
Q

Midfollicular Phase (Selection) is characterized by

A

Characterized by selection of one dominant follicle from the cohort of growing follicles that were stimulated by FSH.

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13
Q

Here the ovary is the least hormonally active and so serum levels of estradiol and progesterone are lower

A

Follicular

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14
Q

This phase is characterized by rapid follicular growth

A

Late Follicular Phase (Dominance)

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15
Q

Luteal phase begins

and ends on

A

on the day of the LH surge and ends at the onset of the next menses.

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16
Q

Ovulation takes place 36-40hr after

A

the LH surge.

17
Q

The secretory activity and functional lifespan of the CL is dependent on

A

appropriate LH support (14 days). Unless implantation occurs

18
Q

what happens if implantation occurs

A

HCG from the developing embryo rescues the CL, involution occurs.

luteal phase defects can become a problem because women don’t get to this point

19
Q

what happens in the late luteal phase if implantation does not occur

A

There is a decline in progesterone, estradiol and inhibin. The reduction in estradiol restores the ability of the pituitary to respond to GnRH signals. The GnRH pulse frequency causes a predominance of FSH secretion. The increase in FSH during this phase is key in initiating recruitment of follicles for the ensuing cycle. It appears

20
Q

Early Luteal Phase

A

prior to ovulation the granulosa cells enlarge and accumulate a yellow pigment (lutein). During the 3 days following ovulation LH transformed granulosa cells and theca cells luteinize and become a structure known as the corpus luteum CL. This transient endocrine organ secretes progesterone and its function is to prepare the estrogen primed endometrium for implantation of the fertilized ovum.

21
Q

cervix would feel softer and more open during

A

follicular phase

22
Q

the fall of this hormone leads to menstrual cycle

A

progesterone

23
Q

fertilization usually occurs at this location in the fallopian tube

A

ampullary portion

24
Q

theca cells are associated with

A

LH

25
Q

corpus lutetium produces

A

progesterone

get’s endometrium ready to support fertilized ovum

26
Q

why is the Luteal phased more predictable

A

that’s how long the corpus lutetium can survive

27
Q

what happens if implantation occurs

A

on the 14th day the embryo will take over with hcG

28
Q

endometrium in the follicular phase

A

proliferative phase

cervical mucus in thinner and clearer to facilitate the passage of sperm

29
Q

the leuteal phase is known as the

A

secretory phase
progesterone is responsible for making endometrial lining mature and ready for an ovum

thick mucus

30
Q

cramps are associated with

A

the presence of prostoglandins

31
Q

what is the physiology behind the shedding of the endometrium caused by the fall in progesterone

A

vessels constrict cause loss of blood supply

combination of endometrium blood and dish