OSCE PREP Flashcards
Hx needed for vaginal complaint (6)
- Personal hygiene – soaps, perfumes, douching
- Sexual activity – use of lubricants, condoms, etc.
- Medications that may alter vaginal pH or flora
a. Oral contraceptive pills, antibiotics - Underlying medical illness – diabetes, HIV
- History of STD
- Use of synthetic undergarments or tight clothing
what would you use if suspecting a yeast infection
KOH smear
non-sexually transmitted diseases
Candidiasis (Candida albicans)
Bacterial vaginosis (Gardnerella vaginalis)
Bartholin’s gland cyst/abscess
Mycoplasma hominis and Ureaplasma urealyticum
STDs
i. Trichomoniasis (Trichomonas vaginalis)
Gonorrhea (Neisseria gonorrhoeae)
Chlamydia (Chlamydia trachomatis)
Herpes simplex virus (HSV)
Syphilis
Human papillomavirus (HPV)
Human immunodeficiency virus (HIV)
Presentation of yeast infection
- Intense vulvar pruritis
- White “cottage cheese” vaginal discharge
- Vulvar, vaginal erythema
- Burning sensation of the vulva; dysuria
- May be vulvar excoriations
- Extensive erythema and edema may indicate underlying systemic illness
Vaginal Discharge dx tests for yeast infection
- Thick, white, curdlike, cheesy
- pH ≤ 4.5
- Buds and hyphae on wet mount and KOH prep
- Vaginal secretions may also be cultured for definitive diagnosis
manage
- Treat all patients with Candida infections
- Control underlying medical illness if present
- Discontinue offending medications
- Avoid douching, nonabsorbent undergarments, tight clothing such as pantyhose
- Not typically sexually transmitted
Topical (intravaginal) tx for yeast infect
a. OTC or Rx imidazoles
b. 85-95% cure rate
c. Combining with steroids for itching – a good idea?
systemic treatment for yeast infection
a. Oral fluconazole (Diflucan) 150mg po x 1
b. Oral itraconazole 200mg po bid x 1 day
yeast infection tx for pregnant pts
a. Avoid imidazoles in the first trimester
b. Nystatin vaginal tabs 100,000 units qhs x 2 weeks
MCC of bac vag
i. Caused by bacteria Gardnerella vaginalis
ii. Most common cause of symptomatic bacterial infections
BV sxs
- Malodorous, nonirritating vaginal discharge
- “Fishy” smell more noticeable after sexual intercourse
- May be found incidentally on well woman exam if asymptomatic
- Not considered sexually transmitted infection
a. Women who are not sexually active rarely present with BV - Watery vaginal DC and petechiae on cervix
pH of BV
vii. pH >4.5
what other tests would you want to confirm BV
Wet mount shows Clue cells
Numerous stippled or granulated epithelial cells
Adherence of bacteria to cell membrane
when would you treat BV
only sx or pregnant women
non pregnant tx of BV
Metronidazole 500mg po bid x 7 days
Metronidazole vag gel: 1 (5g) applicator qhs x 5 d
Clindamycin vaginal ovules 100mg qhs x 3 d
pregnant tx of BV
Metronidazole 500mg po bid x 7 days
Clindamycin 300mg po bid x 7 days
presentation of trichomons
- Persistent, copious vaginal discharge, usually without vulvar pruritis
- Worse after menstruation and during pregnancy
- Dysuria may be associated if vulvitis present
- Vaginal erythema with strawberry spots
a. Multiple small petechiae on vaginal epithelium
Dx tests for trich
- Profuse, greenish, extremely frothy, thin
- May be foul smelling
- pH >5.0
- Wet mount increased PMN leukocytes and motile flagellates (trichomonads)
- Culture and DNA probes for definitive diagnosis
Tx for Trich
- Treat sexual partners simultaneously and avoid unprotected sex until treatment is finished
- Metronidazole 2g po x 1 or 500mg po bid x 7 days
sxs of gonorrhea
- Most women (85%) are asymptomatic
- Purulent vaginal discharge, urinary frequency and dysuria, perineal or rectal discomfort
- May cause conjunctivitis, arthritis, pharyngitis
- On PE: erythematous vulva, vagina, cervix, urethra with purulent discharge
Tx of gonorrhea
- Treat partner concurrently and abstain from sexual contact for 7 days after start of treatment
- Treat presumptively for Chlamydia infection
- Test patient for syphilis; consider HIV testing
- Ceftriaxone 125mg IM x 1 dose or Cefixime 400mg po x 1 dose
a. PLUS Azithromycin 1g po x 1 or Doxycycline 100mg po bid x 7 days for Chlamydia coverage
smelly, strawberry cervix, green frothy dischar
Trichomoniasis