Regulation of Gene Expression Flashcards
Gene Expression
Genes (operons) transcription can be turned on off based on environmental and internal cues
Allows for cell specialization—>unique structure of a cell that allows it to carry out functions
Operons
A group of genes that can be turned on or off
3 parts
1. Promoter: where RNA polymerase can attach
2. Operator: the on and off switch
3. Genes: code for related enzymes in pathway
Types of operons
Repressible (on to off): transcription is usually on, but can be repressed
Inducible (off to on): transcription is usually off, but can be induced
trp operon
-Controls synthesis of tryptophan in bacteria
-Transcription is active
-Can be turned off by yep repressor
-Allosteric enzyme is only active when tryptophan binds
Too much tryptophan—>More likely to bind ti repressor—>Repressor active (no transcription)
*visual in notes
lac operon
-controls synthesis of lactase
-Transcription is off
-A lac repressor is found to operator (allosterically active)
Inducer: allolactose (turns on transcription, binds to repressor)
*visual in notes