Regulation of Cardiac Output and Blood Pressure Flashcards

1
Q

Preload can become raised due to

A

Fast filling time and increased venous return

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2
Q

Contractility can become raised due to

A

Sympathetic stimulation
Epi and norepi
high intracellular calcium ions
high blood calcium levels
thyroid hormones
glucagon

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3
Q

Afterload can become raised due to

A

Increased vascular resistance
Semilunar valve drainage

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4
Q

Preload can be decreased due to

A

decreased thyroid hormones
decreased calcium ions
high or low potassium ions
high or low sodium
low body temperature
hypoxia
abnormal pH balance
drugs

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5
Q

Contractility can become lowered due to

A

Parasympathetic stimulation
acetylcholine
hypoxia
hyperkalemia

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6
Q

Afterload can become lowered due to

A

Decreased vascular resistance

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7
Q

What factors affect heart rate?

A

Increase (Positive chronotrope)-
Sympathetic input
Hormones, such as thyroid hormone

Decrease (Negative chronotrope)-
Parasympathetic input

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8
Q

Total Peripheral Resistance is a product of these three factors

A

Blood viscosity
Total blood vessel length
Vessel diameter (main factor)

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9
Q

The amount of blood ejected by each ventricle in 1 minute is

A

Cardiac output

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10
Q

Equation(s) for CO

A

CO = HR x SV
CO = BP / TPR

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11
Q

There are four main factors that affect the CO

A

Heart Rate
Contractility
Preload
Afterload

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12
Q

Equation for Blood pressure

A

BP = CO x TPR

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13
Q

The SA node is the _____ mechanism for controlling CO.

A

Intrinsic

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14
Q

Neural control of CO and BP (extrinsic)

A

Rapid: Neural control of vessel diameter, heart rate, stroke volume

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15
Q

Chemical/hormone control of CO and BP (extrinsic)

A

Intermediate to long-term:
Renin-Angiotensin II system
Renin-Aldosterone system
Antidiuretic Hormone (ADH)

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16
Q

Three areas of the vasomotor center (neural control)

A

Vasoconstrictor
Vasodilator
Sensory

17
Q

Vasoconstrictor Area- Neurons originating here extend down the spinal cord and ____

A

excite preganglionic sympathetic fibers.

18
Q

The Sensory Area is Located in the ___

A

Nucleus of Tractus Solitarius

19
Q

When needed, the lateral portions of the Vasomotor center transmit _____ to increase heart rate and contractility

A

excitatory impulses through the sympathetic nerve fibers

20
Q

Through the Autonomic Nervous System, the Vasomotor Center regulates these three things

A

HR, SV, and TPR

21
Q

Sensory info from ____ receptors enters the Nucleus of Tractus Solitarius from ___ and ___

A

Baroreceptors; Glossopharyngeal and vagus

22
Q

The rate of firing from the baroreceptors progressively ____ with increasing blood pressure

23
Q

The Baroreceptor Reflex results in _____ by decreasing sympathetic outflow and increasing parasympathetic outflow from the CNS

A

decreased blood pressure

24
Q

When arterial blood pressure falls well below normal, these receptor cells are hypoperfused, resulting in low O2, elevated CO2, and elevated H+. Signals are transmitted via the glossopharyngeal and vagus nerves which excite the Vasomotor Center

A

Chemoreceptors

25
Chemoreceptors increase BP due to
increased TPR and increased CO
26
What is the CNS Ischemic Response?
Decreased blood flow due to hypotension results in increasing levels of CO2 and H+ in the medulla, This has a direct effect of stimulating the sympathetic fibers in the Vasomotor Center, resulting in an increase in blood pressure.
27
In the RAA System, _____ in the walls of the Afferent Arterioles act as baroreceptors and respond to a drop in blood pressure by releasing Renin
Juxtaglomerular cells