Regulation of Cardiac Output and Blood Pressure Flashcards
Preload can become raised due to
Fast filling time and increased venous return
Contractility can become raised due to
Sympathetic stimulation
Epi and norepi
high intracellular calcium ions
high blood calcium levels
thyroid hormones
glucagon
Afterload can become raised due to
Increased vascular resistance
Semilunar valve drainage
Preload can be decreased due to
decreased thyroid hormones
decreased calcium ions
high or low potassium ions
high or low sodium
low body temperature
hypoxia
abnormal pH balance
drugs
Contractility can become lowered due to
Parasympathetic stimulation
acetylcholine
hypoxia
hyperkalemia
Afterload can become lowered due to
Decreased vascular resistance
What factors affect heart rate?
Increase (Positive chronotrope)-
Sympathetic input
Hormones, such as thyroid hormone
Decrease (Negative chronotrope)-
Parasympathetic input
Total Peripheral Resistance is a product of these three factors
Blood viscosity
Total blood vessel length
Vessel diameter (main factor)
The amount of blood ejected by each ventricle in 1 minute is
Cardiac output
Equation(s) for CO
CO = HR x SV
CO = BP / TPR
There are four main factors that affect the CO
Heart Rate
Contractility
Preload
Afterload
Equation for Blood pressure
BP = CO x TPR
The SA node is the _____ mechanism for controlling CO.
Intrinsic
Neural control of CO and BP (extrinsic)
Rapid: Neural control of vessel diameter, heart rate, stroke volume
Chemical/hormone control of CO and BP (extrinsic)
Intermediate to long-term:
Renin-Angiotensin II system
Renin-Aldosterone system
Antidiuretic Hormone (ADH)