Regulating Gene Expression Flashcards

1
Q

protein coding sequences make up — % of the genome.

a. 20
b. 80
c. 0.5
d. 1.5

A

d. 1.5% of genome

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2
Q

our nuclear genome is supplemented by the [….] genome which codes for 13 protein coding genes and 24 RNA coding genes.

A

mitochondrial

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3
Q

euchromatin shows up as […] bands with giemsa stain, is rich in [….and…] nucleotides, and replicates in […..] phase of mitosis. Composed of 80% active genes.

heterochromatin shows up as […] bands with giemsa stain, is rich in [….and…] nucleotides, and replicates in […..] phase of mitosis. Has relatively few active genes!

A

light band,
G and C nucleotides.
early S-phase

dark bands
A and T nucleotides
late S phase

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4
Q

house keeping genes are associated with […] expression, as opposed to regulated expression which is tightly controlled in response to signalling.

A

constitutive

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5
Q

what is a spliceosome

A

large ribonucleoprotein complex that splices primary transcripts to remove introns

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6
Q

gene expression requires an [….] conformation of chromatin. DNA acetylation is associated with the [….] conformation and DNA methylation is associated with the [….] conformation.

A

open
open
closed.

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