Regulación B2 Flashcards

1
Q

Ligando de CTLA3

A

B7

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2
Q

Célula en la que se expresa CTLA4

A

LT regulador

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3
Q

Fx de CTLA4

A

Inhibe activación de LT virgen (inducción)

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4
Q

En dónde actúa CTLA4

A

OLS

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5
Q

Ligando de PD-1

A

PDL-1 y 2

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6
Q

Células en las que se expresa PD-1

A

LT efector

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7
Q

Fx de PD1

A

Inactivar al LT efector

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8
Q

Molécula que es capaz de realizar inhibición por contacto

A

CTLA4

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9
Q

Cómo funciona CTLA4

A

Favorece endocitosis de B7

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10
Q

Cómo se induce la activacón de IDO (idolamina -2,3 dioxigenasa)

A

Por la interacción entre Treg y APC

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11
Q

Garantiza la no respuesta a autoantígenos ubicuos y se realiza en OLP

A

Tolerancia central

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12
Q

Garantiza la no respuesta a autoantígenos específicos, realizada en OLS

A

Tolerancia periférica

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13
Q
A
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