Reflexes, Spinal Cord, SCI (10) EXAM 3 Material Flashcards
Extrafusal fibers
Ordinary skeletal muscle fibers
Intrafusal fibers
Muscle spindle
Golgi Tendon Organ
lies in the junction of the muscle and tendon
Muscle spindle
lies parallel to muscle
What does the muscle spindle do?
Provides information on length and rate of length change in muscle
(stretching and how fast)
What type of afferents does the muscle spindle contain?
Ia and II afferents
Ia is faster than II
Where does the muscle spindle send information to?
Brain and SC (via DCML tract)
What information does the golgi tendon provide?
Information regarding muscle contraction
What type of afferents does the golgi tendon organ contain?
Ib afferents AND gamma motor neurons
Where does the golgi tendon send information to?
Brain and SC (via DCML tract)
Two types of LMNs:
- Alpha
2. Gamma
How can the alpha motor neurons be stimulated?
Ia afferents: from muscle spindle
Ib afferents: from golgi tendon organ (GTO)
UMNs from the brain and/or brainstem
What is the golgi tendon organ sensitive to?
Contraction of muscle and muscle tension
T or F: There is motor neuron innervation in the golgi tendon organ?
False, no alpha motor neuron innervation
What does stretching the golgi tendon organ cause to happen?
Straightens collagen fibers, squeezing and distorting the Ib axons, triggering an action potential
What afferents are firing when a muscle is stretched?
Ia and II (muscle spindle)
What afferents are firing when a muscle length is shortened?
Ib (golgi tendon organ)
What is the smallest behavioral unit controlled by the NS?
Reflexes
What is involuntary and relatively stereotypical?
Reflexes
What varies in location of stimulus and strength of stimulus?
Reflexes
For a reflex to occur, there must be:
- Sensory receptor
- Afferent (sensory)
- Efferent (motor)
- Connection between afferent and efferent
- Muscles (can’t be damaged)
Can reflexes operate without UMN input?
Yes, BUT signals from UMNs typically influence reflexes.
Myotatic Stretch Reflex: Monosynaptic or Dysynaptic?
Monosynaptic (one synapse between sensory and motor (alpha) neurons
Myotatic Stretch Reflex: Ia directly excites what motor neurons? And to what muscle (antagonist or agonist)?
Alpha motor neurons
Agonist muscle
(Causes contraction)
Myotatic Stretch Reflex: Ia causes inhibition of which muscle (agonist or antagonist)?
Antagonist
Myotatic Stretch Reflex: Ia causes inhibition of the antagonist muscle through what?
Inhibitory interneuron
Inverse Myotatic Reflex is done through what organ?
Golgi Tendon Organ
Inverse Myotatic reflex: Monosynaptic or Disynaptic?
Disynaptic
Inverse Myotatic Reflex: Golgi Tendon Organ is most sensitive to what? Causes what to fire?
Muscle contraction, causing Ib to fire
Inverse Myotatic Reflex: What inhibits the agonist muscle and through what?
Ib inhibits the agonist muscle through an inhibitory interneuron
Inverse Myotatic Reflex: What excites the antagonist muscle and through what?
Ib excites the antagonist muscle through an excitatory interneuron.
Cutaneous Reflexes are:
Polysynaptic, with interneurons in the reflex arc
In cutaneous reflex, there is:
- Flexor withdrawal
2. Crossed extension
What is a cutaneous reflex caused by?
Cutaneous stimulation
A lesion in the spinal region may interfere with the following:
- Segmental function
2. Vertical Tract Function
Spinal Region Injury: Segmental Function
Interfere with function only at the level of the lesion
Spinal Region Injury: Vertical Tract Function
Result in loss of function below the level of the lesion
Segmental lesions at spinal cord interferes with function where?
Only at the level of the lesion
Dermatome
Specific area of skin innervated by a single dorsal root
Myotome
Specific muscle or muscle group innervated by a single ventral root
Lesion to Dorsal Root of C5-
Sensory:
Loss, atypical
Lesion to Dorsal Root of C5-
Motor:
Fine
Lesion to Dorsal Root of C5-
Reflexes:
Areflexia
Lesion to Dorsal Root of C5-
Below the level of the lesion:
Fine, didnt impact tracts going up and down
Lesion to LMNs at C5-
Sensory:
Fine
Lesion to LMNs at C5-
Motor:
Weakness (if some)
Paralysis (if all)
Lesion to LMNs at C5-
Reflexes:
Areflexia
Lesion to LMNs at C5-
Below the level of the lesion:
Only have effect at specific segment
Lesion to C5 nerve-
Myotome effect
Paralysis of C5 myotome (elbow flexors)
Lesion to C5 nerve-
Dermatome effect
Loss of all sensory information from C5 dermatome
Vertical Tract Lesions: Loss of communication where?
To and/or from the spinal levels BELOW the lesion
Vertical Tract Lesion: Signs of damage occur where?
BELOW the level of the lesion
Vertical Tract Lesions-
Motor signs:
UMN signs (hyper-reflexia, hypertonia, paralysis)
Brown Sequard Syndrome: Segmental Loss where?
AT level of lesion
Brown Sequard Syndrome: Segmental Loss, Motor (C5):
Loss of elbow flexors
Brown Sequard Syndrome: Segmental Loss, Sensory (C5)
Loss of dermatome
Brown Sequard Syndrome: Segmental Loss, Reflexes (C5)
Areflexia
Brown Sequard Syndrome: Vertical Tract Loss where? (C5)
BELOW level of lesion
Brown Sequard Syndrome: Vertical Tract Loss, Sensory? (C5)
STT –> contralateral and below
DCML –> ipsilateral and below
Brown Sequard Syndrome: Vertical Tract Loss, Reflexes?(C5)
Hyperflexia (same side)
Brown Sequard Syndrome: Vertical Tract Loss, Motor?(C5)
Paralysis Ipsilateral and below
Immediately after spinal cord injury: Bleeding
Bleeding into injured areas leads to swelling, which compresses and damages axons
Immediately after spinal cord injury: Release of free…
Release of free radicals break up cell membranes
Immediately after spinal cord injury: What invades the site and damages the tissue?
Macrophages
Immediately after spinal cord injury: What forms scar tissue?
Astrocytes
Astrocytes do what in a spinal cord injury immediately after injury?
Form scar tissue
Immediately after spinal cord injury: Spinal Shock
Cord functions below lesion are lost or depressed
Areflexia (no reflxes) happens where Immediately after spinal cord injury?
(somatic and autonomic) at and below level of injury
Within weeks or months after a spinal cord injury:
Most people experience some recovery of function in the cord
Within weeks or months after a spinal cord injury: Muscle tone changes to
hypertonicity and hyperactive reflexes (below the level of the lesion)
Within weeks or months after a spinal cord injury: Are there sensory, motor and autonomic impairments? If so, where?
Yes, below the level of the lesion
Within weeks or months after a spinal cord injury: does the neurologic deficit change or stay the same?
Once the lesion is stable (no more bleeding, etc) the neurologic deficit does not change
Tetraplegia:
Loss or impairment in motor and/or sensory function in the cervical segments of the spinal cord resulting in functional impairment in the arms, trunk, legs and pelvic organs
Paraplegia:
Loss or impairment in motor and/or sensory function in the thoracic, lumbar or sacral segments of the cord resulting in impairment in the trunk, legs and pelvic organs and SPARING of the ARMS
Loss or impairment in motor and/or sensory function in the thoracic, lumbar or sacral segments of the cord resulting in impairment in the trunk, legs and pelvic organs and SPARING of the ARMS
Paraplegia
Loss or impairment in motor and/or sensory function in the cervical segments of the spinal cord resulting in functional impairment in the arms, trunk, legs and pelvic organs
Tetraplegia
Spinal cord injuries are classified by two criteria:
- Whether the injury is complete or incomplete
2. The neurological level of injury
Complete SC injury:
A total lack of sensory and motor function in the lowest sacral segment
A total lack of sensory and motor function in the lowest sacral segment
Complete SC Injury
Incomplete SC Injury:
Preservation of sensory and/or motor function in the lowest sacral segment
Preservation of sensory and/or motor function in the lowest sacral segment
Incomplete SC Injury
What is the term used by OTs and PTs; the lowest segment at which strength of key muscles is grade 3+ of 5 or above on manual muscle testing and pain sensation is intact?
Functional level
Neurologic Level:
The most caudal point on the spinal cord with typical sensory and motor function bilaterally.
The most caudal point on the spinal cord with typical sensory and motor function bilaterally.
Neurologic Level
Is it unusual to have a discrepancy between the lowest typical motor level and the lowest typical sensory level?
No, it is not unusual.
What determines sensory level?
Dermatomes
Key muscles controlled at: C5
What are they important for?
Biceps and Deltoid
Important in eating, facial care, brushing teeth
Key muscles controlled at: C6
What are they important for?
Wrist extensors
Grasp / Tenodesis
Key muscles controlled at: C7
What are they important for?
Elbow extensors
Transferring from chair to wheelchair
Key muscles controlled at: C8-T1
What are they important for?
Finger flexors and finger abductors
Grasp
SCI Prognosis:
Hard to predict (variable)
SCI Prognosis: Axons
Axons in spinal cord fo not functionally regenerate