Reflexes Flashcards

1
Q

Bainbridge Reflex

A

Increase in HR following IVF bolus

induced by centralization of blood volume with VC or change in body position
 Reflex also appears to mediate HR s assoc with respiratory sinus arrhythmia

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2
Q

Reverse Bainbridge Reflex

A

may cause bradycardia in face of hypotension during spinal, epidural anesthesia DT increase in venous capacitance, decreased CVP

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3
Q

Bainbridge Reflex: stimulus

A

distention of vena cavae/ RA DT increase in central blood volume.

Detected by atrial stretch receptors (mainly atrial B MR) at junction of vena cavae in RA, in pulmonary veins.

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4
Q

Bainbridge Reflex: Afferent Pathway

A

vagal afferents to medullary vagal nuclei; sensory nucleus of vagus: nucleus tractus solitaries.

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5
Q

Bainbridge Reflex: Efferent Pathway

A

inhibition of vagal PNS outflow to SA node (decrease in ADH release).
 Nucleus ambiguous contains cell bodies for vagal motor neurons to cardiac ganglia

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6
Q

Benzold-Jarish Reflex

A

bradycardia, apnea, hypotension during severe hypovolemia when ventricle empty

AKA coronary chemo reflex

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7
Q

BJR: stimulus

A

Stimulation of ventricular chemoreceptors and mechanoreceptors

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8
Q

BJR: Afferent

A

Stimulation sent through C-fibers to the vagus nerve to the vasomotor portions of the brainstem (NTS)

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9
Q

BJR: Efferent

A

decreased sympathetic outflow (afferent fibers of BJR have a tonic inhibitory effector on vasomotor tone; stimulation leads to decreased vasomotor tone)

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10
Q

BRR

A

Increased BP, decreases HR

blood pressure sensed at carotid sinus, aortic sinus MR from distension

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11
Q

BRR: Afferent

A

Aortic sinus mechanoreceptors signal through Vagus nerve (CNX), carotid body sinus MR signal through glossopharyngeal nerve (CN IX) to nucleus of solitary tract (NTS) then to ventral medulla

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12
Q

BRR: Efferent

A

Medulla signals increases in PSNS activity (release more ACh), decreases SNS activity at SA node to increases HR

Opposite effect with hypotension/increased SNS tone to increase HR

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13
Q

Branham Reflex

A

Hypertension followed by decrease in HR

Compression or excision of an AV fistula (ex: PDA ligation) resulting in a transient hypertension –> decreased HR

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14
Q

Branham: Afferent

A

Vagus n. to NTS

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15
Q

OCR: afferent

A

short, long ciliary nerves merge with ophthalmic division of trigeminal nerve, ciliary ganglion –> Gassenan ganglion –> nucleus of trigeminal, vagus nerve

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16
Q

OCR: efferent

A

Vagal fibers increase tone to SA node

17
Q

Dive Reflex

A

Apnea, decreased heart rate, severe vasoconstriction

Stimulated by submergence of snout of aquatic animal

18
Q

Dive Reflex: Afferent

A

Fibers innervating paranasal areas (anterior nasal mucosa, innervated by infraorbital N, anterior ethmoidal nerve (AEN) from maxillary/ophthalmic divisions of trigeminal)

Send fibers to trigeminal sensory complex.

Projections sent to medullary dorsal horn (MDH) of spinal trigeminal nucleus relay autonomic pathways.

19
Q

Dive Reflex: Efferent Pathway

A

Parasympathetic vagus nerve stimulated to SA node.
 Neurons in rostral ventrolateral medulla (RVLM) increase sympathetic nerve discharge on peripheral vasculature.
 Inhibition of respiration from somatostatin neurons in pre-botzinger complex, ventral respiratory column, retrotrapezoid nucleus silenced

20
Q

Anrep Effect

A

Increase in aortic pressure = positive inotropic effect

21
Q

Bayliss Effect

A

Stretch of vascular SmM –> muscle cox, increased resistance

Result: blood flow toward normal

22
Q

Atrial Stretch R Reflex

A

Atrial distension = release of ANP

ANP = diuretic activity, VD, aldosterone secretion, endogenous antagonist of AGTII

+/- sinus tachycardia, SVT

23
Q

Vasovagal reflex

A

decrease in venous return to heart - sinus bradycardia, hypotension

DT hypovolemia, orthostatic, compression of CdVC, regional ax

24
Q

Craniocardiac Reflex

A

Stimulation of cranial nerves (I, II, V) = bradycardia, hypotension

25
Q

Branham: Efferent

A

Inhibition of sympathetic outflow to SA node

25
Q

Oculocardiac Reflex

A

Compression of eye –> bradycardia

26
Q

Hering-Breuer

A

Lung inflation arrests inspiration
Lung deflation initiates inspiration

Vagus N mediated

27
Q

Pulmonary chemo reflex

A

Stim of C fiber endings (juxtapulmonary capillary R/J R) by tissue damage, fluid accumulation and accumulation of cytokines = sinus bradycardia, hypotension, shallow breathing, apnea, BC, mucous secretion

28
Q

Venorespiratory reflex

A

increased RAP = increased in RR

29
Q

Vagovagal Reflex

A

Afferent, efferent pathways in vagus nerve eg stimulation or irritation of larynx or trachea by laryngoscope, etc