Reducing addiction Flashcards

1
Q

how does drug therapy work on a biological level

A

interact with receptors and enzymes in the brain to reduce cravings or the desire to engage in an activity

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2
Q

what are the three types of drug treatments

A

aversives
agonists
antagonists

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3
Q

out of the three drug treatments which prevent withdrawal symptoms

A

agonists

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4
Q

what do aversives do

A

produce unpleasant consequences if taken with specific drugs eg vomiting and nausea

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5
Q

what principle does aversives based off

A

counter conditioning - replacing pleasant associations with unpleasant ones

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6
Q

what are the three ways to reduce addiction

A
  • drug therapy
  • behavioural interventions
  • CBT
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7
Q

what are agonists in simple terms

A

drug substitutes

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8
Q

how do agonists work

A

act as a less harmful replacement for the drug on which people are dependent

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9
Q

how are agonists less harmful than the original drug

A

have fewer side effects and involve a gradual and controlled withdrawal

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10
Q

how do agonists work on a biological level

A

bind to the same neuron receptors as the addictive drugs and produce a similar effect

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11
Q

how do agonists allow for a gradual and controlled withdrawal

A

there is a gradual reduction in dosage

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12
Q

how do antagonists work

A

prevent the drug of dependence from having its usual effects

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13
Q

how do antagonists work on a biological level

A

block the neural receptor sites

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14
Q

what type of treatment is needed alongside antagonists

A

therapies that tackle the psychosocial causes of the addiction

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15
Q

what do drug therapies for nicotine addiction usually involve (the 2 types)

A
  • nicotine replacement therapy
  • pharmacological interventions (medication)
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16
Q

what type of drug therapies is nicotine replacement therapy

A

agonists

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17
Q

how does NRT work

A

gradually releases nicotine into the bloodstream at lower levels than in a cigarette and without other harmful chemicals in the smoke

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18
Q

what does NRT help the individual control

A

cravings
their mood
prevent relapse

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19
Q

how does NRT work on a biological level

A

causes dopamine release in the nucleus accumbens just like if the person smoked

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20
Q

how does NRT get a person off of their nictonine addiction

A

overtime the dosage of nicotine is reduced in stregnth so the patient can withdraw

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21
Q

how long does NRT usually take

A

2-3 months

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22
Q

what are the different types of NRT

A

nicotine patches, sprays, gum

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23
Q

what are the two medications used for nicotine addictions

A
  • varenicline
  • bupropion
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24
Q

what are varenicline and bupropion

A

nicotine free pulls that reduce a persons craving and withdrawal symptoms and chances of relapse

25
Q

what is it about varenicline and bupropion that people like

A

being nicotine free means they dont increase heart rate and blood pressure

26
Q

how does varenicline work on a biological level

A

attaches to many of the nicotine receptors in a smokers brain

27
Q

what type of drug therapy is varenicline

A

partial agonist

28
Q

what effect does varenicline have

A
  • less intense, continual release of dopamine across the whole day
  • if a cigarette is had, it blocks the nicotine from acting on receptors so no positive effect is felt
29
Q

how what does bupropion do

A

inhibits the reuptake of dopamine

30
Q

what effect do drug treatments have on gambling

A

reduce the urges and craivns to gamble as well as the symptoms of depression or anxiety

31
Q

what are the two drug treatments for gambling addictions

A
  • opioid antagonists
  • antidepressants
32
Q

name the example of an opioid antagonists

A

naltrexone

33
Q

name the example of an antidepressant

34
Q

what effect do opioid antagonists have

A

enhance the release of GABA

35
Q

what effect does increasing the release of GABA have biologically

A

reduces the release of dopamine in the NAc

36
Q

how does reducing dopamine release reduce gambling urges

A
  • no pleasure from gambling
  • reduces the intensity and frequency of gambling urges
37
Q

what effect do antidpressants have biologically

A

increase serotonin levels, improving gambling behaviour

38
Q

how does higher serotonin levels improve gambling behaviour

A
  • reduces the symptoms of depression and anxiety
  • reduces the impulsivity associated w gambling
39
Q

what assumption do behavioural interventions work on

A

the assumption that addictive behaviours are learned so can be reduced by changing the consequences of the behaviours

40
Q

what do behavioural interventions intend to do to addictive behaviour

A

replace pleasant consequences with unpleasant consequences so the motivation to smoke/gamble is reduced

41
Q

what are the two types of behavioural intervention

A
  • aversion therapy
  • covert sensitisation
42
Q

what is aversion therapy also known as

A

overt sensitisation

43
Q

which behavioural intervention uses real unpleasant associations

A

aversion therapy

44
Q

which behavioural intervention uses imagined unpleasant associatiosn

A

covert sensitisation

45
Q

what happens during aversion therapy

A

the patient engages in the addictive behav whilst being exposed to something unpleasant

46
Q

give examples of the unpleasant things used in aversion therapy

A

taking a drug that makes them feel nauseous, a bad smell, mild electric shocks

47
Q

what theory are behavioural interventions based on

A

classical conditionig

48
Q

how can aversion therapy be used for alcohol addiction

A

patient given an aversive drug causing nausea when alcohol is consumed

49
Q

give an example of an aversive drug for alcohol addiction

A

disulfiram

50
Q

what effect does disulfiram have on the body

A

interferes with the metabolising of alcohol causing servere nausea

51
Q

what is the conditioned response from consuming alcohol

A

nausea and vomiting

52
Q

how does aversion therapy work on gambling addictions

A

when phrases related to gambling addiction are read out, the patient recieves an electric shock

53
Q

why does aversion therapy for gambling addiction involve more preparation

A
  • patient needs to write down some phrases related to gambling, some not
  • patient needs to preselect duration and intensity of the shock
54
Q

how is covert sensitisation different to aversion therapy

A

unpleasant stimulus is imagined (in vitro) rather than reality (in vivo)

55
Q

how are the unpleasant stimuli for covert sensitisation imagined

A

pictured in the persons mind

56
Q

what must the imagined unpleasant stimulus do to the patient

A

cause feelings of considerable discomfort or anxiety

57
Q

what level of discomfort must the aversies cause

A

pain but no permanent damage

58
Q

how can covert sensitisation be used for alcohol addiction

A

patients could imagine themselves feeling intense nausea, vomiting, embarrassing themselves