Red Cell Antigens and Immune-mediated hypersensitivity

Question 1

Define type II hypersensitivity reaction.

Question 2

Describe the pathogenesis of acute transfusion reaction.

Question 3

What are the 4 requirements for hemolytic disease of newborn?

Question 4

In what species is hemolytic disease of newborn fairly common?

Question 5

How many red cell antigens are internally recognized in the dog?

Question 6

Which blood type is the most common in the dog?

Answer 6

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Question 7

Which DEA is the most common in the dog?

Question 8

Which DEA is considered universal donor? universal recipient?

Question 9

How would neonatal hemolytic disease occur in the dog?

Question 10

What’s the most common DEA expressed in the dog?

Question 11

Which DEA in the dog can have naturally occurring antibody?

Question 12

How is serological testing done for canine blood?

Question 13

How many blood types are in cats?

Question 14

What’s the most common blood type in cats?

Question 15

What’s the most common blood antigen in the cat?

Question 16

How important is it to blood type cats?

Question 17

How common is neonatal hemolytic disease in cats?

Question 18

How is blood typing performed in cats?

Question 19

Define hemophagocytic syndrome?

Question 20

What’s the criteria for hemophagocytic syndrome?

Question 21

What are the 3 ways that type II hypersensitivity from drugs can destroy red blood cells?

Question 22

How do infections lead to type II hypersensitivity reactions to red blood cells?