Allergic Diseases

Question 1

Define the hygiene hypothesis.

Question 2

How does fiber in the diet play a role in allergies?

Question 3

How does a healthy microbiota suppress inflammation in the intestinal wall?

Question 4

What is the pathophysiology of anaphylaxis?

Question 5

What’s the shock organ in the dog? in the cat?

Question 6

What are the clinical signs of a dog experiencing anaphylaxis?

Question 7

What are the clinical signs of a cat experiencing anaphylaxis?

Question 8

What are the major mediators of anaphylaxis in the dog? in the cat?

Question 9

What’s the normal response when oral tolerance is intact?

Question 10

What happens when the oral tolerance breaks down?

Question 11

What’s the usual clinical signs to allergic airway disease in cats? in dogs?

Question 12

How is the IgG serum level different between intrinsic and extrinsic atopic dermatitis?

Question 13

What’s “allergic triad”?

Question 14

Which TH cytokines are elevated in intrinsic/ extrinsic allergic dermatitis?

Question 15

What’s the role of thymic stromal lymphopoietin in atomic dermatitis?

Question 16

Name 3 significant mediators associated with pruritus.

Question 17

Which cytokine causes severe pruritus in dogs?

Question 18

How does oclacitinib work?

Question 19

What does IgE serum level indicate for dogs with allergic dermatitis?

Question 20

What’s anaphylacatoid?

Question 21

What are some possible factors that can lead to the development of atopic dermatitis?

Answer 21

skin barrier dysfunction
environment

Question 22

Which is the most important allergic skin disease due to parasites?

Question 23

What are the clinical signs associated with eosinophilic granuloma complex?

Question 24

What’s the pathogenesis of erythema and wheal formation in hypersensitivity reaction?

Question 25

Is serum antigen or intradermal testing preferred for atopic dermatitis? why?

Question 26

How does corticosteroids work in type I hypersensitivity reaction?

Question 27

How does epinephrine, isoprenaline, salbutamol, methoxamine, and phenylephrine work in type I hypersensitivity reaction?

Question 28

What’s the role of antihistamines in controlling allergic diseases in animals?

Question 29

What are some treatment options for atopic dermatitis?

Question 30

What’s the main mechanism of action of immunotherapy for dogs with atopic dermatitis?