recreational drugs Flashcards
what is an agonist drug?
a drug that activates the synaptic receptor sites
what is an antagonist drug?
1) a drug that does not activate the synaptic receptor sites
what is does the reuptake inhibitor do?
blocks the reuptake of the neurotransmitters so more neutransmitters remain in the synpase, increases its action
what does the reward pathway involve?
the reward pathway involves activities that lead to an elevated level of dopamine and alleviates rhythms in the brain’s reward system
how does the reward system link to drug taking?
1) neurotransmitters are released into the mesolymbic pathway when you experience pleasure
2) different parts of the pathway have dopamine receptors that causes you to take that drug again
what makes up the mesolymbic pathway?
1) the hippocampus
2) the amygala
3) the nucleus accumbens
what does the nucleus accumbens do?
controls motor functions
what are the short term effects on cocaine?
- increased behaviour and alertness
what are the long term effects of cocaine?
- decreased serotonin
- decreased dopamine
- decreased need to eat and sleep
- hypersensitivity
how does heroin impact neurotransmitters?
- increases the amount of dopamine in the reward pathways in the brain
- boosts the activation of dopaminergic synapses
- the wearing off of dopamine leads to dysphoria
how does cocaine impact neurotransmitters?
- exaggerates changes caused by noradrenaline and dopamine
- increases alertness and causes euphoria
- blocks the reuptake of dopamine in the presynaptic neuron so more dopamine remains in the synapse
what are the short term effects of heroin?
- feeling of warmth
- reduction of pain
- slows down mental functions, breathing and heart rate
what are the long term efffect of heroin?
- physical and psychological dependence
- withdrawal symptoms as the brain adapts to the heroin
- less endorphine is being produced = addiction
how does amphetamine impact neurotransmitters?
- increases the levels of noradrenaline and dopamine by reversing the reuptake process in the synaptic gap
- reduces the action of glutamine
what are the short term effects of amphetamine?
- increased heart rate and blood pressure
- reduced fatigue and feelings of happiness
- decreased appetite