Receptors and What They Doo Doo

Question 1

Name the tissues that express the receptor, the receptor type, and the physiologic effect of binding…

α1

Answer 1

smooth muscle

Gq

contracts smooth muscle

Question 2

Name the tissues that express the receptor, the receptor type, and the physiologic effect of binding…

α2

Answer 2

presynaptic side of sympathetic nerve varicosities

Gi (inhibitory)

inhibits release of NE from sympathetic nerves (auto-inhibitory)

Question 3

Name the tissues that express the receptor, the receptor type, and the physiologic effect of binding…

β1

Answer 3

heart, juxtaglomerular cells

Gs

increases contractility

Question 4

Name the tissues that express the receptor, the receptor type, and the physiologic effect of binding…

β2

Answer 4

smooth muscle - ex. in the lungs

Gs

relaxes smooth muscle

Question 5

Name the tissues that express the receptor, the receptor type, and the physiologic effect of binding…

β3

Answer 5

fat cells and bladder

Gs

in fat cells, binding promotes lipid breakdown

in the bladder, binding promotes bladder relaxation