Receptors Flashcards

1
Q

What transmitters act on Alpha 1 receptors?

A

Norepinephrine
Epinephrine
Dopamine

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2
Q

What transmitters act on Alpha 2 receptors?

A

Norepinephrine
Epinephrine

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3
Q

What transmitters act on Beta 1 receptors?

A

Norepinephrine
Epinephrine
Dopamine

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4
Q

What transmitters act on Beta 2 receptors?

A

Epinephrine

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5
Q

What transmitters act on depamine receptors?

A

dopamine

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6
Q

Where are the Alpha 1 receptors located?

A

Eyes
blood vessels
male sex organs
prostate capsule
bladder

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7
Q

Where are the alpha 2 receptors located?

A

nerve terminals (always presynaptic)

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8
Q

Where are beta 1 receptors located?

A

heart and kidney

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9
Q

Where are beta 2 receptors located?

A

lung
uterus
arterioles of heart, lung, skeletal muscle
liver

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10
Q

Where are the dopamine receptors located?

A

kidney

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11
Q

What is the function of the Ocular A1?

A

dilate pupil

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12
Q

What is the function of a1 receptors in the blood vessels?

A

vasoconstriction

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13
Q

What function does the alpha 1 receptors have on male sex organs?

A

ejaculation

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14
Q

What function does Alpha 1 receptors have on the smooth muscle of the bladder?

A

contraction

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15
Q

What function dose alpha 2 have on the presynaptic nerve terminals?

A

regulates neurotransmitter release or prevents release when there is too much transmitter in the synaptic gap.

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16
Q

What is the function of beta 1 receptors on the heart?

A

increases HR and force of contraction

17
Q

What is the function of beta 1 receptors on the kidney?

A

release renin to blood, which helps with vasoconstriction and increases BP.

18
Q

What is the function of beta 2 receptors on the lungs?

A

bronchial dilation

19
Q

What is the function of beta 2 receptors on the uterus?

A

relaxation of uterine smooth muscle

20
Q
A
21
Q

What is the function of beta 2 receptors on the arterioles of the heart/lungs?

A

vasodilation

22
Q

What is the function of beta 2 receptors on the skeletal muscle?

A

contraction

23
Q

What is the function of beta 2 receptors on the liver and skeletal muscle?

A

glycogenolysis

24
Q

What is the function of dopamine receptors on the kidney?

A

dilates renal blood vessels to increase perfusion

25
Q

What are the transmitters of the Peripheral nervous system (PNS)?

A

ACh
NE
Epi

26
Q

What are the 3 cholinergic receptor subtypes?

A

Nicotinic M
Nicotinic N
Muscarinic

27
Q

What transmitter can act on all three cholinergic receptors?

A

Acetylcholine

28
Q

What is the location of the Cholinergic receptor Nicotinic N?

A

cell bodies of post-ganglionic neurons in the SNS and PSNS

29
Q

What is the location of the Cholinergic receptor Nicotinic M?

A

skeletal muscle

30
Q

What is the location of the Cholinergic receptor Muscarinic?

A

all organs regulated by the PSNS and sweat glands

31
Q

What is the function of Nicotinic N on the cell bodies of post-ganglionic neurons in SNS & PSNS?

A

promotes ganglionic transmission in all ganglia of SNS and PSNS

32
Q

What is the function of Nicotinic N on the adrenal medulla?

A

it promotes the release of Epi from the adrenal medulla

33
Q

What function does Nicotinic M have on the skeletal muscle?

A

contraction of the skeletal muscle

34
Q

What is the function of the muscarinic receptors on all organs of the PSNS and sweat glands?

A

elicits a response from the organ involved
ex. decreases HR, contract ciliary eye muscle, urination, contraction of iris sphincter

35
Q

What is an agonist?

A

a drug that binds to a receptor and causes the same reaction as the transmitter that normally binds to that receptor.

36
Q

What is an antagonist?

A

A drug that binds to a receptor and prevents the reaction that would occur if the normal transmitter binds.