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Receptors Flashcards

1
Q

Muscarinic M1

A

CNS

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2
Q

M2

A

Heart

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3
Q

M3 (5)

A

Git
Bronchi
Bladder
Gland secretion
Circular muscles of iris

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4
Q

Nicotinic Nn(3)

A

CNS
ganglion
Adrenals

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5
Q

Nm

A

Neuromuscular junction

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6
Q

M1 G_

A

Gq

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7
Q

M2 G_

A

Gi/o

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8
Q

M3 G_

A

Gq

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9
Q

Carboprost acts on

A

PGF2 ALFA
Synthetic

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10
Q

Dinoprost acts on

A

PGF2 ALFA
Natural

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11
Q

Dinoprostone acts on

A

PGE2

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12
Q

Misoprostol acts on

A

PGE1

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13
Q

What maintains patency of ductus arteriosus

A

PGE1

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14
Q

Typical antipsychotics act on

A

D2 receptors

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15
Q

ATypical antipsychotics act on

A

5HT2 receptors

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16
Q

Opioid mu receptors

A

M miosis
U urine retention
S sedation
C constipation
A analgesia
R respiratory depression
I increase muscle rigidity
N negate bile flow by contraction of sphincter of oddi
E euphoria

17
Q

Opioid kappa receptor

A

C constipation
A analgesia
Antiprurituc
P psychomimetic dysphoria

18
Q

Delta opioid receptor

19
Q

GABA A

A

Brain
Chloride ion channel
Anti epileptic

20
Q

GABA B

A

Spinal cord
Open potassium channel
Muscle relaxant

21
Q

Benzodiazepines act on

A

GABA A receptors
Bind between alfa and gamma subunit and increase FREQUENCY of chloride channel opening

22
Q

Barbiturates increase _ of chloride channel opening

23
Q

Z compounds selectively act on _ of GABA receptors

A

Alfa 1 subunit

24
Q

H1 and H2

A

Gq
Gs
Both are Postsynaptic

25
H3 and H4
Gi H3 on Presynaptic and H4 on leukocytes
26
H1 receptor mechanism and effects
Increases Calcium Bronchoconstriction Vasodilation Git contraction Wakefullness in Hypothalamus Decrease appetite Itching
27
H2 mechanism
Increases cAMP Increases HR and contraction HCl in stomach

Pharma (6 decks)

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