Receptors Flashcards
Muscarinic M1
CNS
M2
Heart
M3 (5)
Git
Bronchi
Bladder
Gland secretion
Circular muscles of iris
Nicotinic Nn(3)
CNS
ganglion
Adrenals
Nm
Neuromuscular junction
M1 G_
Gq
M2 G_
Gi/o
M3 G_
Gq
Carboprost acts on
PGF2 ALFA
Synthetic
Dinoprost acts on
PGF2 ALFA
Natural
Dinoprostone acts on
PGE2
Misoprostol acts on
PGE1
What maintains patency of ductus arteriosus
PGE1
Typical antipsychotics act on
D2 receptors
ATypical antipsychotics act on
5HT2 receptors
Opioid mu receptors
M miosis
U urine retention
S sedation
C constipation
A analgesia
R respiratory depression
I increase muscle rigidity
N negate bile flow by contraction of sphincter of oddi
E euphoria
Opioid kappa receptor
C constipation
A analgesia
Antiprurituc
P psychomimetic dysphoria
Delta opioid receptor
Analgesia
GABA A
Brain
Chloride ion channel
Anti epileptic
GABA B
Spinal cord
Open potassium channel
Muscle relaxant
Benzodiazepines act on
GABA A receptors
Bind between alfa and gamma subunit and increase FREQUENCY of chloride channel opening
Barbiturates increase _ of chloride channel opening
Duration
Z compounds selectively act on _ of GABA receptors
Alfa 1 subunit
H1 and H2
Gq
Gs
Both are Postsynaptic
H3 and H4
Gi
H3 on Presynaptic and H4 on leukocytes
H1 receptor mechanism and effects
Increases Calcium
Bronchoconstriction
Vasodilation
Git contraction
Wakefullness in Hypothalamus
Decrease appetite
Itching
H2 mechanism
Increases cAMP
Increases HR and contraction
HCl in stomach
