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Pharma > Receptors > Flashcards

Receptors Flashcards

1
Q

Muscarinic M1

A

CNS

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2
Q

M2

A

Heart

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3
Q

M3 (5)

A

Git
Bronchi
Bladder
Gland secretion
Circular muscles of iris

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4
Q

Nicotinic Nn(3)

A

CNS
ganglion
Adrenals

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5
Q

Nm

A

Neuromuscular junction

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6
Q

M1 G_

A

Gq

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7
Q

M2 G_

A

Gi/o

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8
Q

M3 G_

A

Gq

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9
Q

Carboprost acts on

A

PGF2 ALFA
Synthetic

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10
Q

Dinoprost acts on

A

PGF2 ALFA
Natural

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11
Q

Dinoprostone acts on

A

PGE2

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12
Q

Misoprostol acts on

A

PGE1

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13
Q

What maintains patency of ductus arteriosus

A

PGE1

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14
Q

Typical antipsychotics act on

A

D2 receptors

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15
Q

ATypical antipsychotics act on

A

5HT2 receptors

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16
Q

Opioid mu receptors

A

M miosis
U urine retention
S sedation
C constipation
A analgesia
R respiratory depression
I increase muscle rigidity
N negate bile flow by contraction of sphincter of oddi
E euphoria

17
Q

Opioid kappa receptor

A

C constipation
A analgesia
Antiprurituc
P psychomimetic dysphoria

18
Q

Delta opioid receptor

A

Analgesia

19
Q

GABA A

A

Brain
Chloride ion channel
Anti epileptic

20
Q

GABA B

A

Spinal cord
Open potassium channel
Muscle relaxant

21
Q

Benzodiazepines act on

A

GABA A receptors
Bind between alfa and gamma subunit and increase FREQUENCY of chloride channel opening

22
Q

Barbiturates increase _ of chloride channel opening

A

Duration

23
Q

Z compounds selectively act on _ of GABA receptors

A

Alfa 1 subunit

24
Q

H1 and H2

A

Gq
Gs
Both are Postsynaptic

25
Q

H3 and H4

A

Gi
H3 on Presynaptic and H4 on leukocytes

26
Q

H1 receptor mechanism and effects

A

Increases Calcium
Bronchoconstriction
Vasodilation
Git contraction
Wakefullness in Hypothalamus
Decrease appetite
Itching

27
Q

H2 mechanism

A

Increases cAMP
Increases HR and contraction
HCl in stomach

Pharma (6 decks)

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