Autocoids Flashcards

1
Q

2nd gen H1 blockers are DOC for

A

Urticaria
Also for rhinitis(non allergic) . For allergic, steroids are DOC

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2
Q

Most potent H1 blocker 2nd gen

A

Desloratidine

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3
Q

Least sedating H1 blocker

A

1st gen- chlorpheniramine
2nd gen- fexofenadine

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4
Q

Topical antihistamines

A

Azelastine
Epinastine
Alcaftadine
Olopatadine
Levocarbastine

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5
Q

DOC for hereditary angioedema

A

C1 esterase inhibitor for treatment
Danazol for prophylaxis
EACA prophylaxis before surgery

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6
Q

5HT1a agonist presynaptic

A

Buspirone
Anxiolytics

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7
Q

5HT 1b/1d agonist
Found in 5th CN

A

Triptans
Decrease CGRP release, treat migrane attack

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8
Q

5HT2 antagonist uses

A

Cyproheptidine
Serotonin syndrome
Prophylaxis migrane
Carcinoid syndrome
Cold urticaria

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9
Q

Flibanserin use
(5Ht2 antagonist)

A

Hypoactive sexual desire disorder

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10
Q

Neurokinin 1 inhibitors

A

Aprepitant
Doc for late onset chemo induced vomiting

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11
Q

Side effect of 5ht3 antagonist
(Ondansetron)

A

Hypotension
QT prolongation

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