Recent Seizure/Epilepsy Flashcards

1
Q

what should you always order in patients presenting with first time seizure

A

Na
glucose
CT head

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2
Q

what is status epilepticus

A

more than 30 minutes of continuous seizure activity, or recurrent seizures withough full recovery

seizure lasting more than 5 min should be presumed to be status and be treated as such

immediate treatment is the key for reducing mortality

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3
Q

define seizure

A

abnormal and unregulated electrical neural discharge that interrupts normal brain function and causes altered awareness, abnormal sensations, involuntary movements and/or convulsions

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4
Q

what is the difference between an epileptic and a nonepileptic seizure

A

epilepsy is a chronic brain disorder involving recurrent (2 or more) seizures without a reversible disorder or stressor

non epileptic seizures can be caused by a temporary disorder or stressor i.e metabolic disorders, CNS infections, CV disorders, drugs, withdrawal

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5
Q

in a child less than 2, what is the most likely seizure etiology

A

developmental defects

metabolic disorders

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6
Q

in a child ages 2-14, what is the most likely seizure etiology

A

idiopathic

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7
Q

in adults what is the most likely seizure etiology

A
trauma
etoh withdrawal 
tumours
strokes
idiopathic
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8
Q

in the elderly what is the most likely seizure etiology

A

tumours

strokes

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9
Q

how do you classify seizures

A

generalized or partial

generalized have no focal onset, and affect both hemispheres simultaneously

partial have a focal or localized onset

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10
Q

how do you classify partial seizures

A

either simple, which maintains awareness, or complex, which loses awareness

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11
Q

what are the types of generalized seizures

A

tonic clonic

atonic (sudden loss of tone)

absence (brief lapse of awareness)

tonic

myotonic

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12
Q

what drugs can cause seizures

A

etoh or benzo withdrawal

cocaine

LSD

methanol

ethylene glycol

TCAs

insulin

prescription drugs

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13
Q

what infections can cause seizures

A

febrile seizures
meningitis
encephalitis

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14
Q

what are metabolic problems that can cause seizures

A

hypoglycemia, hyponatremia, hypocalcemia

non ketotic hyperglycemic, hyper osmolar coma

hyperthyroidism

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15
Q

what are structural causes of seizures

A

mass
stroke
trauma
congenital malformations

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16
Q

list some seizure mimics

A
migraines
syncope
stroke/TIA
psychogenic
movement disorders
night terrors
panic attacks

*absence of post ictal phase suggests a seizure mimic

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17
Q

what are some complications of seizures

A

aspiration, hypoxia–> brain injury, lactic acidosis, rhabdomyolysis–> ARF

18
Q

what triggers to ask about

A
sleep deprivation
flickering lights
menses
hyperventilation
voiding/defecating
19
Q

what to ask about the pre-ictal phase?

A

aura? (simple partial)
automatisms? (complex partial)

if triggered by intense emotions/exercise, and occurs along with diaphoresis, lightheadedness, pallor–> likley syncope

20
Q

what to ask about the ictal period

A
loss of awareness
aura
abnormal motor activity
muscle tone (rigid vs flaccid)
facial involvement (head or eye deviation, tongue biting, excess blinking)
symptom lateralization
incontinence
tongue biting
automatisms

numbness
weakness
CV risk factors for TIA

visual aura, N/V, pounding headache suggests migraine

waxing/waning movements, pelvic thrusting, sobbing or moaning during event suggests psychogenic

21
Q

what is Todds paralysis

A

hemiplegia post ictally–suggestive of focal onset

transient paralysis lasting less than 48 hours

22
Q

red flags for seizures

A

status epilepticus
sudden or “worst ever” headache (SAH)
stiff neck, fever (meningitis)
focal neuro signs

23
Q

what meds to ask about specifically in seizure history

A
psychotropics
benzos
theophylline
bupropion
meperidine
24
Q

what do you HAVE to address when someone has a seizure/gets diagnosed with epilepsy

A

DRIVING

also occupation/risks

25
what exam should be done in seizure evaluation
full neuro, including CN, tone, strength, DTRs, sensory and cerebellar/gait also vitals
26
what blood tests should you order in seizure evaluation
``` CK beta hcg--eclampsia? tox lytes troponin PROLACTIN ```
27
why do you order prolactin when evaluating seizures
if measured 10-20 min after event, and it is elevated, it can be helpful in distinguishing generatlized tonic clonic seizure or complex partial from psychogenic seizures *cannot be used to distinguish between seizures and syncope
28
who should get an EEG
urgent for status recommended for all patients with new seizure
29
how to manage acute seizure
ABCs, VS, prevent injury and aspiration ensure safe environment put patient in recovery position give O2 antiepileptics--> phenytoin, phenobarbital, VPA
30
what are the seizure precautions to discuss
no swimming or bathing alone avoid heights avoid baths no fire no driving until evaluated by a neurologist (should have normal CT head and EEG)
31
what are automatisms
lip smacking chewing sucking
32
what is jacksonian march
one body part is initially affected, followed by spreading to other body parts
33
how to screen for seizures
``` lost time unresponsive even if someone touches you smell burning or other auras automatisms periods of confusion/post ictal simple partial seizures with dysphagia, fear, deja vu ```
34
how do you discuss epilepsy with a patient with questions
relatively common treatable though not curable most people can lead safely normal lives especially if taking meds and following basic precautions
35
things to be careful doing when you have epilepsy
``` heights swimming operating heavy machinery boating locked bathrooms/bedrooms ```
36
how do you counsel around epilepsy meds
need to take even when seizure free establish a routine discuss SEs close f/up to monitor drug levels many drug interactions--when buying OTC drugs, check with pharmacists to ensure no interactions because can increase or decrease levels in blood anti epileptics can also interfere with other drugs like the OCP
37
what particular type of med do anti epileptics interfere with
OCP
38
when can you try being off meds
when youve been seizure free for a few years
39
how should you counsel female epilepsy patients
phenytoin, carbamazepine and phenobarbital all increase metabolism of OCP risk of birth defects (take folate 4-6 mg daily during child bearing years) evaluate fetal neural tube defects if pregnant
40
effect of alcohol on epilepsy
lowers seizure threshold