Recap Flashcards
Addiction definition
A chronic relapsing disorder, characterised by compulsive drug seeking, continued use despite harmful consequences
Dependence definition
A condition when one can only function in the presence of a drug. Characterised by withdrawal symptoms when drug use is stopped
Tolerance definition
A condition where higher doses of drugs are needed to achieve the desired effect
What is physical dependence
This is demonstrated when there is presence of withdrawal symptoms when the drug is not taken
Psychological dependence
Psychological dependence occurs when a drug becomes central to a persons thoughts emotions and activities.
Stimulants
-Cause increased awareness , more awake , energetic
-in caffeine, nicotine, cocaine, amphetamines
Depressants
-more relaxed, lower inhibition, reduce concentration and coordination
-in alcohol, benzodiazepines and GHB
Hallucinogens
-they alter thinking, time perception and emotions
-in LSD, NBOMes and Mushrooms
Dissociative anaesthetics
-hallucinations, change emotions, change in consciousness
-in ketamine , nitrous oxide , PCP
Anabolic steroids
-increase muscle size, increase strength, increased performance
-in testosterone, oxymethylone, stanozlol
What are pharmacokinetics?
-What does the body do with the drug
-the movement or the drug through the body
Pharmacodynamics
-What the drug does to the body
-body’s response to the drug
4 main processes in pharmacokinetics
ADME (absorption, distribution, metabolism and elimination)
What is bioavailability ?
The fraction of drug that reaches systematic circulation in an unchanged form
Bio transformation meaning ?
Biochemical modification or degradation through specialised enzymatic actions
