Recalls Fri-Feb23 Flashcards
A protein strand…. M strand encodes the NSm nonstructural protein and
the G1 (viral attachment) and G2 proteins, and the L strand
encodes the L protein (polymerase)
Nonstructural protein 1
●FLAVIVIRIDAE
● Enveloped, icosahedral, non-segmented, (+)ssRNA
●Aedes mosquito bites / Sexual and vertical transmission possible
● Causes conjunctivitis, low-grade pyrexia, muscle and joint pain, malaise, headache, and itchy rash in 20% cases
●First identified in Uganda in 1947.
Zika virus
Infectious mononucleosis (IM)
● Under Cytomegalovirus
● EBV ( Epstein-Barr Virus) / HHV-4
● ‘Kissing disease’
● Transmitted through saliva
● Genital warts (condyloma acuminata)
● Respiratory tract papillomas
● Most common viral STD
HPV 6 and 11
● Most common AIDS malignancy
● HHV-8 / Human Herpes 8
● Malignancy of the vascular endothelial cells
● Dark/violaceous plaques or nodules representing vascular proliferations
Kaposi’s sarcoma
● Poxviridae (Largest RNA virus)
● Brick-shaped virus
● Only disease that has been eradicated from the face of the earth
● Guarnieri bodies
Smallpox
● HHV-6: ROSEOLA / EXANTHEM SUBITUM / SIXTH DISEASE
● Nagayaman spots: erythematous papule on soft palate and base of uvula
HHV 6 and 7
● Varicella-Zoster Virus
● ( VZV / HHV-3
● Varicella / Chicken pox
● HERPES ZOSTER / SHINGLES —> Reactivation of Zoster Virus
HHV3/ Varicella-Zoster Virus