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MRCPsych Part A > Recall 3 > Flashcards

Recall 3 Flashcards

1
Q

Which receptor responsible for Tardive Dyskinesia

A

Supersensitive D2

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2
Q

Clozapine related myocarditis most specific marker

A

Eosinophilia

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3
Q

Glycine MOA

A

NMDA receptor

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4
Q

Sodium Valproate congenital malformation rate

A

8 - 12 %

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5
Q

Receptor for Postural hypotension

A

Alpha 1 antagonism

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6
Q

Paroxetine SE

A

Sweating, sexual dysfunction, withdrawal Sx

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7
Q

Topiramate SE

A

Weight Loss

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8
Q

Drugs that cause least sexual side effects

A

Vortioxetine / Mirtazapine / Agolmelatine

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9
Q

Cariprazine MOA

A

D2, D3, 5HT1a agonist

Partial antagonist at 5ht2a/b

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10
Q

Most selective AP for D2

A

Amisulpiride

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11
Q

Partial agonist of nicotinic receptors

A

Varenicline

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12
Q

Anti Psychotic with longest half life >50 hours

A

Aripiprazole

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13
Q

AP injection most likely to cause NMS

A

Haloperidol

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14
Q

Best therapy for HIV induced cognitive impairment

A

Anti-retroviral therapy

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15
Q

Changing the magnetic field over the scalp?

A

Transcranial magnetic stimulation

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16
Q

Direct current given with saline pads?

A

Transcranial direct stimulation

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17
Q

Ideomotor apraxia

A

Unable to use tools

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18
Q

Ideational apraxia

A

Unable to follow sequences

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19
Q

Imaging for white matter tract lesion localisation

A

DTI - MRI

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20
Q

Reciprocal inhibition is seen in…

A

Systematic desensitisation

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21
Q

Which factor least responsible for delayed speech?

Small family / large family / immigration / smoking in pregnancy / alcohol in pregnancy

A

Small family

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22
Q

What can be done to reduce group think?

A

Open debate

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23
Q

What stage of moral development is child in stage?

A

Social order

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24
Q

CBT + Rogerian theory is what therapy?

A

Motivational interviewing

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25
Q

Erikson stage at 22?

A

LOVE - Intimacy and isolation

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26
Q

Brain default network structure

A

Posterior cingulate cortex

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27
Q

NT in multitasking

A

Dopamine

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28
Q

Anti-NMDA R encephalitis antibody better from CSF or Serum

A

CSF

29
Q

Which inflam marker for depression

A

IL - 6

30
Q

Which developmental condition shows multifactorial genetics

A

Autism

31
Q

Trinucleotide repeat of X syndrome

A

Fragile X - CGG

32
Q

Brain region involved in PTSD

A

Amygdala

33
Q

Gaming disorder length of time

A

12 months

34
Q

Which NT increased in REM?

A

ACh

35
Q

Which NT in non REM increased?

A

NA

36
Q

Excessive laughter term

A

Hyperklepexia

37
Q

Lithium plus HTN - add what?

A

Atenolol

38
Q

ADHD gene

A

DRD4

39
Q

Term for person with fear of heights and at height

A

Implosion

40
Q

DSM V - what changed about schizophrenia

A

Subtypes discarded

41
Q

Term for finding a new meaning to a belief in the process of delusion?

A

Apophany

42
Q

Which neurons use glutamate as NT

A

Pyramidal and Granular

43
Q

Which neurons are efferent to the cortex?

A

Pyramidal

44
Q

Stages of Piaget development

A

Sensorimotor - object permanence
Preoperational - language, imagery, play
Concrete operational - conservation of volume
Formal operational - test hypothesis

45
Q

Three terms associated with piaget

A

Schema
Assimilation
Accomodation

46
Q

Epigenic principle whom

A

Erikson - personality develops in a set order

47
Q

Levinson stages?

A

Whole life with some 5 years overlap between each stage.

Age based rather event based

48
Q

Sexual dysfunction APs and why

A

Risperidone - Prolactin
Haloperdiol - Prolactin
Clozapine - Alpha 1 antagonism, ACh antagonism

49
Q

What did Bleuler say with respect to Schizophrenia?

A

4 x As

Autism
Ambivalence
Association (loosening)
Affective blunting

50
Q

Valproate MOA

A

GABA modulation, NMDA antagonist, Na channel inhibition

51
Q

Marcia 4 Identity types and how classified?

A

Explored options & committed - Identity Achievement
Explore options & not committed - Moratorium
Not explored options & Committed - Foreclosure
Not explored & not committed - Diffusion

52
Q

Cluttered Speech - which condition

A

Fragile X

53
Q

dysguesia - is what from what drug?

A

Abnormal taste - se lithium

54
Q

Aripiprazole MOA

A

5HT1a, 5HT2a, Partial d2 antagnoism

55
Q

Reversible MAOI

A

Moclobecamide

56
Q

Irreversible MAOI

A

Phenylzine

57
Q

Puberty Female

Menarche Age
Age range
Average age onset
Precocious puberty age

A

Menarche - tanner 4
8-14 years
11
8

58
Q

Least cardiotoxic AD/TCA

A

Lofepramine

59
Q

Duloxetine use

A

Generalised anxiety disorder

Pain disorder

60
Q

Therapy where people admire feeling powerless/helpless

A

CBT

61
Q

Ketamine MOA

A

NMDA antagonist

62
Q

Tetrabenzine highest receptor affinity

A

Reversible VMAT 2 inhibitor

63
Q

Sleep terror occur in which phase sleep? Child waking up agitated

A

Sleep terrors occur in nrem3 - delta waves

64
Q

Difference between somatisation vs hypochondriasis

A

Somatic symptoms versus abnormal beliefs about illness

65
Q

Vortioextine moa

A

5HT1A agonist
5HT1B agonist

5ht3, 5ht7 antagonist

66
Q

Amisulpiride MOA

A

D2/D3

67
Q

Non dominant Parietal lobe lesion (rt) cvads

A

Constructional apraxia
Visuospatial defect
Dressing apraxia
Anosognosia
Prosapognosia
HemiSpatial neglect

68
Q

Dominant temporal lesion

A

Wernickes apahasia
Memory disturbance
Auditory agnosia

69
Q

Non dom temporal

A

Auditory agnosia
Emotional recognition issues
Visual memory deficits

MRCPsych Part A (3 decks)

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