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MRCPsych Part A > Recall 2 > Flashcards

Recall 2 Flashcards

APR 2023

1
Q

How can you increase bioavailability of a drug?

A

Change route of administration

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2
Q

Which antipsychotic would increase if taken with lithium?

A

Amisulpride

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3
Q

The term for a a person unable to recall a traumatic experience? Dissociative Amnesia/Dissociative identity disorder/Possession trance disorder

A

Dissociative Amensia

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4
Q

Term for a person unable to recall their personal identity?

A

Dissociative identity disorder

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5
Q

Which power?

A patient stops taking medicines on advice of doctor

A

Expert Power

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6
Q

Which Power?

Group campaign to stop smoking

A

Information power

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7
Q

Which power?

A patient stops taking medicines after discussion of side effects and effects with doctor

A

Information power

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8
Q

Which power?

A patient stops taking medicines after doctor insists they do so?

A

Coercive power

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9
Q

Medical ethics

Team decide not to tell patient about mass on X-ray

A

Paternalism

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10
Q

Medical ethics

Doctor does not prescribe clozapine after previous agranulocytosis

A

Non-maleficence

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11
Q

Medical ethics

Man with depression makes an advanced decision not to have ECT

A

Autonomy

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12
Q

Which describes flash bulb experience?

A

Intense emotion

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13
Q

Which of the following was listed in more than 1 category in ICD 11?

Depression/Anxiety Disorder/Dissociative disorder/factitious disorder

A

Dissociative disorder

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14
Q

Rapid catalytic rate with substrate?

GABA A / COMT / Glutamate

A

COMT

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15
Q

What differentiates Complex PTSD from PTSD

A

Repetitive, intense severe traumatic experiences

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16
Q

Which of the following drugs do not cross the BBB?

Lithium / Aripiprazole / Quetiapine / Amisulpride / RIsperidone

A

Amisulpride - active transport

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17
Q

Which of the following drugs have poor absorption?

Risperidone / Lurasidone / Asenapine

A

Lurasidone (5-15% PO)

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18
Q

Which of the following drugs increase the risk of Autism?

Carbamazepine / Amisulpiride / Levetiracetam / Sodium Valproate

A

Sodium Valproate

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19
Q

Antiemetic action of Mirtazapine is mediated through which receptor?

A

5HT3

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20
Q

How long does IM Paliperidone monthly depot take to reach max plasma concentration?

A

13 days

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21
Q

Which mechanism does Lithium-induced polyuria occur?

Inc sensitivity to ADH / changes in Cl signalling / Inc Na excretion / Dec expression of aquaporins

A

Dec Aquaporin expression - which leads to diabetes insipidus

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22
Q

Likely changes to be seen in types of anorexia

Vomiting type

A

Parotid swelling

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23
Q

Likely changes to be seen in types of anorexia

Laxative type

A

Dec colonic motility

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24
Q

Which part of the brain is responsible for attention difficulties in ADHD?

A

DLPFC

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25
Q

Radiological finding in schizophrenia?

A

Reduced volume of striatum - unsure, likely temporal lobes structures

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26
Q

Which part of the brain is responsible for auditory hallucinations?

A

Superior temporal gyrus - superior temporal lobe

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27
Q

Which antipsychotics have low availability in the brain?

A

Amisulpride/Sulpride

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28
Q

Which structure is activated more during mentalisation in adolescents than in adults?

A

Amygdala

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29
Q

Which scale measures no pain at all to excruciating pain?

A

Semantic

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30
Q

How are purines synthesised and what are they?

A

Guanine & Adenine

Uncommon nitrogen containing compounds

1ry from diet but body synthesis too

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31
Q

What is true about reducing prejudice?

A

Obtaining more information about a class of people

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32
Q

What is courtesy stigma?

A

Stigma by association of someone already stigmatised

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33
Q

What is felt stigma?

A

Felt stigma is the feeling that one will be stigmatised by others due to condition or experience.

Prevents seeking help

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34
Q

What is enacted stigma?

A

The experience of unfair treatment by others

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35
Q

Receptor structure types

GABA A (5 letters)

A

Heteropentomer

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36
Q

Receptor structure types

Glutamate

A

Heterodimer, NMDA, AMPA, Kainate

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37
Q

Receptor structure types

Ionotropic

A

Multimeric

AMPA/NMDA/Kainate

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38
Q

Gait seen in UMN

A

Spastic/Scissor

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39
Q

Gait seen in Normal Pressure Hydrocephalus

A

Magnetic

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40
Q

Gait seen in Cerebellar disease

A

Ataxic

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41
Q

Part of brain most activated in attachment with maternal and infant?

A

Amygdala and hippocampus

42
Q

Receptor that cocaine works on?

A

Dopamine transporter

43
Q

Which recreational drug does Khat mimic?

A

Amphetamine

44
Q

What is the active component of Khat?

A

Cathinone

45
Q

What does the Hayling test asses?

A

Executive function

46
Q

What does part A of trail making test assess?

A

Perceptual - motor speed

47
Q

How long does working memory store information for?

A

30 seconds

48
Q

What is true of bullying x2

A

Bullies prefer the same type of victim
Bullies have less social maturity

49
Q

What needs to be done to clozapine in pregnancy and why?

A

Dose increase due to enzyme induction

50
Q

Test for abstract reasoning

A

Similarities, proverbs, sentence completion test

51
Q

Tower of London tests what?

A

Executive function

52
Q

Which organism is implicated in development of OCD?

A

S. pyogenes

53
Q

What stage is conservation seen?

A

Concrete operational

54
Q

What is inductive reasoning? What about the white swans?

A

Specific to general - Making generalised conclusions based on specific scenarios

55
Q

What is deductive reasoning? What about the white swans?

A

General to specific - think white swans - Backing up a generalised statement with specific scenarios

56
Q

SSRI with anxiogenic metabolite

A

Fluoxetine

57
Q

Anti depressant that does not act as prodrug

A

Desipramine

58
Q

Theory that believes consequences of an action determines whether action is good or bad?

A

Punishment

59
Q

Which theorist talked about authority

A

Kohlberg 2nd stage of conventional

60
Q

What is true about the big 5 model of personalities?

A

Biological characteristics

61
Q

The forced swim test is related to which conditon?

A

Depression

62
Q

Re: The psychopathology of illusions

Perception & cognitive / Cognitive and conceptual / conceptual and perceptual / Perceptual and signal processing (bottom up)

A

Perceptual and signal processing (bottom up)

63
Q

Top down theory of perception/illusion

A

Cognition and perception

64
Q

Which is true about agomelatine?

Half life 12 hours / Increases 5HT in synapses / MT antagonist / Extensively metabolised by CYP1A2

A

Extensively metabolised by CYP1A2

65
Q

Anti depressant group with highest affinity to H1 receptors

A

TCAs

66
Q

What is the reason for anomic suicide detailed by Durkheim?

A

Lack of close relationship

67
Q

Term for Exaggerated and catastrophic misinterpretation

A

Hypochondriasis

68
Q

Bright light therapy is used in which rhythm?

Circadian rhythm - diurnal rhythm

A

Circadian Rhythm

69
Q

Which is part of the Papez circuit?

A

Cingulate Cortex & Hippocampus

70
Q

Psychiatric Screening Tool

EPND / MADRS / Hamilton / Montgomery scale

A

EPND

71
Q

Test of premorbid intelligence

A

National Adult Reading Test

72
Q

Genetic condition whose phenotype related to schizophrenia

A

DiGeorge

73
Q

Which of the following do not cause delayed language development?

Migration / maternal smoking / Lack of cognitive stimulation / Large family size / maternal alcohol

A

Migration

74
Q

Neurodegenerative disorder linked to schizophrenia?

MD / Friedrich’s Ataxia / Huntington

A

Huntington

75
Q

Name of prion disease that is not CJD or Kuru?

A

Fatal Familial Insomnia

76
Q

Difference between Ideomotor vs Ideational apraxia

A

An inability to follow out learned tasks when given necessary objects vs inability to follow a sequence of actions in the correct order

77
Q

Deep brain stimulation is most useful for which condition?

Depression / psychosis / ADHD

A

Depression

78
Q

EEG findings in seizure

Typical absence

A

3 hz spike

79
Q

EEG findings in seizure

Atypical absence

A

slow generalised spike and wave <2.5 hz

80
Q

EEG findings in seizure

Focal

A

Focal spike

81
Q

EEG findings in seizure

Myoclonic

A

3 - 6 hz polyspike

82
Q

EEG findings in DT

A

Hyperactive fast trace

83
Q

EEG findings in Alzheimers

A

Reduced A & B, Increased D & T

84
Q

Definition of Neuralation

A

Formation of neural tube

85
Q

Which memory affected in Korsakoff syndrome

A

Episodic

86
Q

Which memory is affected in confabulation

A

Autobiographical memory/ episodic

87
Q

Brain organoid corresponds with which fetal time

A

2nd trimester

88
Q

Kids with ADHD - what behavioural action to help them focus on tasks?

A

Use of small immediate rewards

89
Q

HIV associated neurocognitive disorder in patient who has been on ART for long time, what is seen in blood?

A

High CD8 count

90
Q

Definition of avoidant / restrictive food intake disorder

A

Not preoccupied by weight instead excludes certain food groups from diet

91
Q

What is used in T2 weight MRI

A

Water

92
Q

Ion implicated in Schizophrenia

A

Calcium

93
Q

Alcohol addiction therapy

A

Cue Therapy

94
Q

Stranger anxiety develops when?

A

9 months

95
Q

Which NT is easily disintegrated

A

ACh

96
Q

Disulfiram acts on which enzyme

A

Aldehyde dehydrogenase

97
Q

Which neuroimaging is used to detect D2 occupancy

A

DAT Scan (SPECT)

98
Q

A potent inhibitor of DAT

A

Sertraline

99
Q

Lentiform nucleus made up of what?

A

Putamen and Globus Pallidus

100
Q

Striatum made up of?

A

Caudate and Putamen

101
Q

Which stage and which theory can a child understand the pain of another child

A

Ericksons operational

102
Q

Autoimmune encephalitis target?

A

NMDA

MRCPsych Part A (3 decks)

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