Recall 2 Flashcards by Robert Hafes

How can you increase bioavailability of a drug?

Change route of administration

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Which antipsychotic would increase if taken with lithium?

Amisulpride

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The term for a a person unable to recall a traumatic experience? Dissociative Amnesia/Dissociative identity disorder/Possession trance disorder

Dissociative Amensia

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Term for a person unable to recall their personal identity?

Dissociative identity disorder

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Which power?

A patient stops taking medicines on advice of doctor

Expert Power

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Which Power?

Group campaign to stop smoking

Information power

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Which power?

A patient stops taking medicines after discussion of side effects and effects with doctor

Information power

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Which power?

A patient stops taking medicines after doctor insists they do so?

Coercive power

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Medical ethics

Team decide not to tell patient about mass on X-ray

Paternalism

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Medical ethics

Doctor does not prescribe clozapine after previous agranulocytosis

Non-maleficence

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Medical ethics

Man with depression makes an advanced decision not to have ECT

Autonomy

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Which describes flash bulb experience?

Intense emotion

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Which of the following was listed in more than 1 category in ICD 11?

Depression/Anxiety Disorder/Dissociative disorder/factitious disorder

Dissociative disorder

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Rapid catalytic rate with substrate?

GABA A / COMT / Glutamate

COMT

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What differentiates Complex PTSD from PTSD

Repetitive, intense severe traumatic experiences

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Which of the following drugs do not cross the BBB?

Lithium / Aripiprazole / Quetiapine / Amisulpride / RIsperidone

Amisulpride - active transport

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Which of the following drugs have poor absorption?

Risperidone / Lurasidone / Asenapine

Lurasidone (5-15% PO)

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Which of the following drugs increase the risk of Autism?

Carbamazepine / Amisulpiride / Levetiracetam / Sodium Valproate

Sodium Valproate

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Antiemetic action of Mirtazapine is mediated through which receptor?

5HT3

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How long does IM Paliperidone monthly depot take to reach max plasma concentration?

13 days

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Which mechanism does Lithium-induced polyuria occur?

Inc sensitivity to ADH / changes in Cl signalling / Inc Na excretion / Dec expression of aquaporins

Dec Aquaporin expression - which leads to diabetes insipidus

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Likely changes to be seen in types of anorexia

Vomiting type

Parotid swelling

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Likely changes to be seen in types of anorexia

Laxative type

Dec colonic motility

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Which part of the brain is responsible for attention difficulties in ADHD?

DLPFC

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Radiological finding in schizophrenia?

Reduced volume of striatum - unsure, likely temporal lobes structures

Which part of the brain is responsible for auditory hallucinations?

Superior temporal gyrus - superior temporal lobe

Which antipsychotics have low availability in the brain?

Amisulpride/Sulpride

Which structure is activated more during mentalisation in adolescents than in adults?

Amygdala

Which scale measures no pain at all to excruciating pain?

Semantic

How are purines synthesised and what are they?

Guanine & Adenine Uncommon nitrogen containing compounds 1ry from diet but body synthesis too

What is true about reducing prejudice?

Obtaining more information about a class of people

What is courtesy stigma?

Stigma by association of someone already stigmatised

What is felt stigma?

Felt stigma is the feeling that one will be stigmatised by others due to condition or experience. Prevents seeking help

What is enacted stigma?

The experience of unfair treatment by others

Receptor structure types GABA A (5 letters)

Heteropentomer

Receptor structure types Glutamate

Heterodimer, NMDA, AMPA, Kainate

Receptor structure types Ionotropic

Multimeric AMPA/NMDA/Kainate

Gait seen in UMN

Spastic/Scissor

Gait seen in Normal Pressure Hydrocephalus

Magnetic

Gait seen in Cerebellar disease

Ataxic

Part of brain most activated in attachment with maternal and infant?

Amygdala and hippocampus

Receptor that cocaine works on?

Dopamine transporter

Which recreational drug does Khat mimic?

Amphetamine

What is the active component of Khat?

Cathinone

What does the Hayling test asses?

Executive function

What does part A of trail making test assess?

Perceptual - motor speed

How long does working memory store information for?

30 seconds

What is true of bullying x2

Bullies prefer the same type of victim Bullies have less social maturity

What needs to be done to clozapine in pregnancy and why?

Dose increase due to enzyme induction

Test for abstract reasoning

Similarities, proverbs, sentence completion test

Tower of London tests what?

Executive function

Which organism is implicated in development of OCD?

S. pyogenes

What stage is conservation seen?

Concrete operational

What is inductive reasoning? What about the white swans?

Specific to general - Making generalised conclusions based on specific scenarios

What is deductive reasoning? What about the white swans?

General to specific - think white swans - Backing up a generalised statement with specific scenarios

SSRI with anxiogenic metabolite

Fluoxetine

Anti depressant that does not act as prodrug

Desipramine

Theory that believes consequences of an action determines whether action is good or bad?

Punishment

Which theorist talked about authority

Kohlberg 2nd stage of conventional

What is true about the big 5 model of personalities?

Biological characteristics

The forced swim test is related to which conditon?

Depression

Re: The psychopathology of illusions Perception & cognitive / Cognitive and conceptual / conceptual and perceptual / Perceptual and signal processing (bottom up)

Perceptual and signal processing (bottom up)

Top down theory of perception/illusion

Cognition and perception

Which is true about agomelatine? Half life 12 hours / Increases 5HT in synapses / MT antagonist / Extensively metabolised by CYP1A2

Extensively metabolised by CYP1A2

Anti depressant group with highest affinity to H1 receptors

TCAs

What is the reason for anomic suicide detailed by Durkheim?

Lack of close relationship

Term for Exaggerated and catastrophic misinterpretation

Hypochondriasis

Bright light therapy is used in which rhythm? Circadian rhythm - diurnal rhythm

Circadian Rhythm

Which is part of the Papez circuit?

Cingulate Cortex & Hippocampus

Psychiatric Screening Tool EPND / MADRS / Hamilton / Montgomery scale

EPND

Test of premorbid intelligence

National Adult Reading Test

Genetic condition whose phenotype related to schizophrenia

DiGeorge

Which of the following do not cause delayed language development? Migration / maternal smoking / Lack of cognitive stimulation / Large family size / maternal alcohol

Migration

Neurodegenerative disorder linked to schizophrenia? MD / Friedrich's Ataxia / Huntington

Huntington

Name of prion disease that is not CJD or Kuru?

Fatal Familial Insomnia

Difference between Ideomotor vs Ideational apraxia

An inability to follow out learned tasks when given necessary objects vs inability to follow a sequence of actions in the correct order

Deep brain stimulation is most useful for which condition? Depression / psychosis / ADHD

Depression

EEG findings in seizure Typical absence

3 hz spike

EEG findings in seizure Atypical absence

slow generalised spike and wave <2.5 hz

EEG findings in seizure Focal

Focal spike

EEG findings in seizure Myoclonic

3 - 6 hz polyspike

EEG findings in DT

Hyperactive fast trace

EEG findings in Alzheimers

Reduced A & B, Increased D & T

Definition of Neuralation

Formation of neural tube

Which memory affected in Korsakoff syndrome

Episodic

Which memory is affected in confabulation

Autobiographical memory/ episodic

Brain organoid corresponds with which fetal time

2nd trimester

Kids with ADHD - what behavioural action to help them focus on tasks?

Use of small immediate rewards

HIV associated neurocognitive disorder in patient who has been on ART for long time, what is seen in blood?

High CD8 count

Definition of avoidant / restrictive food intake disorder

Not preoccupied by weight instead excludes certain food groups from diet

What is used in T2 weight MRI

Water

Ion implicated in Schizophrenia

Calcium

Alcohol addiction therapy

Cue Therapy

Stranger anxiety develops when?

9 months

Which NT is easily disintegrated

ACh

Disulfiram acts on which enzyme

Aldehyde dehydrogenase

Which neuroimaging is used to detect D2 occupancy

DAT Scan (SPECT)

A potent inhibitor of DAT

Sertraline

Lentiform nucleus made up of what?

Putamen and Globus Pallidus

Striatum made up of?

Caudate and Putamen

Which stage and which theory can a child understand the pain of another child

Ericksons operational

Autoimmune encephalitis target?

NMDA

Recall 2 Flashcards

APR 2023