Readings (Days 21-40) and Lectures 6-11 Flashcards
Abnormal immune mediated response attacks the meylin nerve coating (oligodendrocytes) and the nerve fibers in the CNS
Multiple Sclerosis
Form of MS in which Relapses and remissions do not occur
Primary-Progressive MS
Most common form of MS
Relapshing-remitting
Form of MS that begins with relapsing-remitting course followed by progression to steady and irreversible worsening of neurologic function
Secondary-Progressive MS
Form of MS that is characterized by a nearly continuous worsening of the disease from the onset without distinct attacks
Primary-Progressive MS
Common sx of MS
paresthesias, minor visual disturbances, weakness, fatigue, sharp, shooting pain, spasticity
slurred or poorly articulated speech with low volume, unnatural emphasis, and slow rate
Dysarthria
Changes in vocal quality including harshness, hoarseness, breathiness, or hypernasal sounds.
Dysphonia
Three bladder dysfunctions with MS
-small, spastic bladder (failure to store)
-flaccid, big bladder (failure to empty)
-dyssynergic bladder (coordination difficulty btwn bladder contraction and sphincter relaxation)
What test is used to diagnose MS?
MRI
Chronic condition characterized by widespread pain that affects multiple body regions and the axial skeleton and has lasted for >3 months.
Fibromyalgia
FM or MPS?
-Tender points at specific cites
-No referred pain patterns
-No tight band of mm
-Fatigue and waking unrefreshed
FM
FM or MPS?
-Trigger points in mm
-referred patterns of pain
-tight band of muscle
-no related fatigue complaints
MPS
What chronic condition typically has its first sx occur in early to middle adulthood and develops after physical trauma such as a MVA or viral infection?
FM
chronic, regional pain syndrome
Myofascial pain syndrome (MPS)
Lie in parallel with muscle fibers and monitor changes in mm length and velocity
muscle spindles
Receptors located at proximal and distal tendinous insertions of mm and monitor tension within mm. They also provide protective mechanism by preventing structural damage to mm in extreme tension situations
golgi tendon organs
receptors within fascia of mm that respond to pain and pressure
free nerve endings
receptors within fascia of mm which respond to vibratory stimuli and deep pressure
pacinian corpuscles
Which pathway is concerned with non-discriminative sensations such as pain, temperature, tickle, itch, and sexual sensations?
Spinothalamic Tracts
Pathway responsible for transmitting discriminative touch, stereognosis, tactile pressure, barognosis, graphesthesia, recognition of texture, two-pt discrimination, kinesthesia, proprio, and vibration
DCML
pain produced by a non-noxious stimuli
Allodynia
complete loss of pain sensitivity
Analgesia
increased sensitivity to pain
hyperalgesia