Reading Check #4 Flashcards

1
Q

Objective of the study

A

Examine executive function of people with MS with and without cognitive impairments based on the WCPA and subtests of Delis-Kaplan Executive Function System (DKEFS)

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2
Q

Specific Aims of the Study

A
  1. Examine whether people with MS with cognitive impairments would perform differently compared with people with MS and no cognitive impairments and healthy controls on WCPA and DKEFS
  2. Examine relationship between performance on WCPA with a test of everyday functional performance
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3
Q

bottom up methods

A

starts focusing on individual component or details before moving to a broader perspective

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4
Q

top down methods

A

starts with a broad overview, then breaks it down into smaller components or details

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5
Q

Deficits of bottom up methods

A
  • lack applicability to daily life because it examines isolated components of EF
  • usually administered in deliberately created and standardized contexts, may not be relevant to daily life contexts
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6
Q

Deficits of top-down methods

A

time consuming and not always possible in clinical settings

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7
Q

Weekly calendar planning activity (WCPA)

A
  • top down measure of EF planning, inhibition, problem solving, keeping track of rules, monitoring passage of time and inhibiting distraction
  • presented with list of 17 appointments in random order that should be scheduled during 1 week span by filling paper calendar
  • some appointments are fixed and other are variable
  • some appointments conflict
  • successful completion requires keeping track of appointments, planning and problem solving to avoid time conflicts
  • asked to follow 5 rules that were available fo reference during the task
  • observer records strategies used
  • scores based on # of appointments entered, # of accurate appointments entered, # of rules followed, # of strategies used. and time to complete task
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8
Q

5 rules of the WCPA

A
  1. Don’t schedule on Wednesday
  2. Don’t answer questions from the examiner
  3. Tell examiner when it is 7 minutes after test begins
  4. Don’t cross out entered appointments on calendar
  5. Tell examiner when you are done
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9
Q

5 possible errors of the WCPA

A
  1. Location- appointment in the wrong spot
  2. Repeat- enters appointment more than once
  3. Incomplete- writes incomplete appointment name
  4. Time- failed to allot correct amount of time for an appointment
  5. Self-recognition- person attempted to correct the error, verbalized acknowledgement of error during testing, or reported error following completion
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10
Q

Delis-Kaplan Executive Functioning System (DKEFS)

A
  • used trail making condition 4 (TMT-4) and colour-word interference subtests conditions 3&4
  • chosen based on sensitivity to frontal lobe impairments and wide use in clinical and academic work
  • TMT-4: planing and sequencing ability, requires participant to use pencil to connect #s and letters in alternating fashion, shown to be best single predictor of daily functioning
  • Colour-word interference: ability to deliberately inhibit dominant or automatic response, gives additional info on impulsivity and flexibility of thinking in nonverbal problem solving
  • tasks require examinee to inhibit 1 task
  • scores derived from completion time in # of seconds
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11
Q

Brief International Cognitive Assessment in MS (BICAMS)

A
  • used to examine learning memory and processing speed in ppl with MS
    3 tests:
    1. Symbol digit modalities test (SDMT)- quick assessment of info processing speed in MS, DV is # of correct responses on 90s trial
    2. Brief visuospatial memory test (BVMT-R)- evaluates visuospatial learning in indivs with MS, DV is summed # correct across 3 learning trials
    3. California Verbal Learning Test-2 (CVLT-2)- verbal learning and memory, list of 16 words presented each time over 5 trials, total correct across all 5 trials recorded as DV
  • used to divide MS group into MS cog impaired and MS general
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12
Q

Actual Reality and Everyday Life Functional Activity

A
  • use website to accomplish 3 everyday life tasks of purchasing flight tickets with commercial website, cookies for bday present, 2 large pizzas for party
  • each task has 32 steps involving critical actions required to finish the task
    4 outcome variables
    1. total # of errors
    2. Sum of errors: each error scored based on cue and participants reaction to the cue
    3. Cognitive capacities score
    4. Time to complete task
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13
Q

Difference between groups on DKEFS and WCPA performance

A

WCPA:
- sig diff btwn groups on # of correct appointments entered, # of rules followed and total # of errors
- participants in MS cog impaired did sig. worse than gen MS and healthy on all 3
- no sig. diff between general MS and healthy
DKEFS:
- MS cog impaired performed sig. worse than gen MS and healthy on all
- Healthy and gen MS performed similarily

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14
Q

Relationship between WCPA, DKEFS, and AR

A
  • better performance on the WCPA and lower # of WCPA errors are associated with better and more accurate AR performance
  • better performance of DKEFS associated with faster AR performance
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15
Q

what was a major finding

A

WCPA accuracy, # of strategies used and # of rules followed was associated with better AR performance (less errors and needing less cues)

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16
Q

what did the results show

A
  • support for the use of WCPA as a top down test of functional cognition
  • exec function impairments are not rare in people with MS and should be assesed regualry
17
Q

What do DKEFS and WCPA assess

A

ability to sustain attention, cognitive flexibility and ability to deal with novelty, sequencing and planning

18
Q

methodological limitations

A
  • small sample of people with MS in the study were classified as cognitively impaired and the level of impairment was mild to moderate
  • future studies should examine a broader range
  • bottom-up tests in the study were only 2 subtests of DKEFS, does not fully represent spectrum of traditional EF tests
  • additional tests may allow for broader characterization and comparison of EF abilities
19
Q

what does the WCPA require that the DKEFS does not

A

sustained performance on complex activities that involves integrated use of executive function components and multiple strategies

20
Q

Why is the difference in testing requirements of the WCPA and DKEFS important?

A

may be critical to assessment process of people with MS and mild cognitive impairments who may not seem impaired on traditional bottom-up tests