Reactions of Epoxides Flashcards
1
Q
Epoxide rings are opened with nucleophiles and acids HZ
A
- The reaction occurs with a backside attack, resulting in trans or anti products
- With nucleophile, the mechanism is SN2, and nucleophilic attack occurs at the less substituted C
- With HZ, the mechanism is between SN1 and SN2, and attack of Z^- occurs at the more substituted C.