Reactions of Epoxides Flashcards

1
Q

Epoxide rings are opened with nucleophiles and acids HZ

A
  1. The reaction occurs with a backside attack, resulting in trans or anti products
  2. With nucleophile, the mechanism is SN2, and nucleophilic attack occurs at the less substituted C
  3. With HZ, the mechanism is between SN1 and SN2, and attack of Z^- occurs at the more substituted C.
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