Carbonyl Chemistry Predict Products

Question 1

Reduction of carbonyl reagents 1

Answer 1

1. NaBH4
2. H2O

Takes away carbonyl and makes the O an OH and adds H to carbonyl carbon

Question 2

Reduction of carbonyl reagent 2

Answer 2

1. LiAlH4
2. H2O

O turns into OH and H adds to carbonyl carbon
Carbonyl is eliminated

Question 3

Reduction of carbonyl reagent 3

Answer 3

H2,Pd/C

O turns to OH and H adds to carbonyl carbon. Carbonyl is gone

Question 4

Organometallics Reagents

Answer 4

Cl or Br(mg)-C grignards
Li-C
Na-Ctriple bond C-R

C is a alkyl/sp3,Alkene/sp2 phenyl
Cross out metal and add whatever is attached at the carbonyl carbon. O on carbonyl turns to OH

Question 5

Protecting group

Answer 5

TBDMSCl or R3SiCl and Base
Protecting group hides the H on the alcohol so the group is added to carbonyl carbon and not OHgroup.

Protecting group replaces H leaves O
Then use TBAF or Bu4NF and “F:-“ to deprotect H comes back to replace the protecting group after group connected to metal was added

Question 6

Deprotecting reagents

Answer 6

TBAF and F:-

Or Bu4NF and F:-