Reaction@arene Flashcards by Ivy Hsieh | Brainscape

Q

Benzene to -NO2

A

@E.S

cHNO3, cH2SO4, 60degree

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Q

-NO2 to -NH2

A

@reduction

Sn, cHCl, reflux
follow by NaOH

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Q

-NH2 to -NH3+

A

@acid-base

-dilute HNO3

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Q

Benzene to -CH3

A

@E.S

-CH3Cl, anhydrous AlCl3, rtp

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Q

-CH3 to -COOH

A

@side chain oxidation

-KMnO4(aq), H2SO4(aq), reflux

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Q

Benzene to COO-

A

@Side chain oxidation

-KMnO4(aq), NaOH(aq), reflux

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Q

Benzene to -X(Cl/Br) +HX

A

@E.S

-X2, anhydrous FeX3/AlX3/Fe fillings

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Q

Benzene to -COCH3

A

@E.S

-CH3OCl, anhydrous AlCl3, rtp

Balance: +HCl

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