Reaction Flashcards

1
Q

Primary mediator of type 1 hypersensitivity reaction is

A

Immunoglobin E (IgE)

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2
Q

Allergy Type 1

  • damaging effects of hypersensitivity to outside antigens
  • most common allergies are type 1
  • atopic genetic predisposed
A

damaging effects of hypersensitivity to outside antigens
most common allergies are type 1
atopic genetic predisposed

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3
Q

which of these are Type 1 common allergies

  • pollen
  • mold
  • fungi
  • foods
  • animals
  • dust
  • everything we encounter in our environment
A

pollen
mold
fungi
foods
animals
dust
everything we encounter in our environment

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4
Q

S/S of allergy

A

watery, runny eyes
runny nose
sneezing
nasal congestion
itchy rash or hives

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5
Q

Anaphylaxis is what

  • immediate type 1 hypersensitivity
  • rapid onset of IgE mediated chemicals
  • induces severe life-threatening allergic reaction
A

immediate type 1 hypersensitivity
rapid onset of IgE mediated chemicals
induces severe life threatening allergic

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6
Q

Common causes of Anaphylaxis

A

food
drug
insect bites

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7
Q

Anaphylaxis S/S: Lungs

  • trouble breathing or noisy breathing
  • coughing, wheezing
  • sneezing
  • congestion
  • tightness of lungs
  • hoarseness
A

trouble breathing or noisy breathing
coughing, wheezing
sneezing
congestion
tightness of lungs
hoarseness

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8
Q

Anaphylaxis S/S: Lungs

  • trouble breathing or noisy breathing
  • coughing, wheezing
  • sneezing
  • congestion
  • tightness of lungs
  • hoarseness
A

trouble breathing or noisy breathing
coughing, wheezing
sneezing
congestion
tightness of lungs
hoarseness

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9
Q

Anaphylaxis S/S: Skin

  • pale or flushed
  • hives or welts
  • itchy skin
  • sweating
A

pale or flushed
hives or welts
itchy skin
sweating

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10
Q

Anaphylaxis S/S: Heart and blood vessels

  • chest pain
  • low BP
  • weak rapid pulse
  • dizziness, fainting
A

chest pain
low BP causing weak, rapid pulse
dizziness, fainting

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11
Q

Anaphylaxis S/S: Mouth

  • swelling of throat, face, lips, or tongue
A

swelling of throat, face, lips, or tongue

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12
Q

Anaphylaxis S/S: Stomach and Digestion

  • abdominal pain
  • nausea, vomiting
  • diarrhea
A

abdominal pain
nausea vomiting
diarrhea

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13
Q

IgE

  • reactions are mediated by antigen-specific IgE and the products of tissue mast cells
A

reactions are mediated by antigen-specific IgE and the products of tissue mast cells

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14
Q

Treatment for Anaphylaxis

A

First line - EPINEPHRINE
Benadryl

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15
Q

Epi-pen

  • light sensitive, keep in storage tube
  • administer in thigh
  • VERY EXPENSIVE
A

light sensitive, keep in storage tube
administer in thigh
VERY EXPENSIVE

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16
Q

Epinephrine Action

  • adrenergic response

Route
- SQ
- IM
- IV

A

SQ:
- onset 5-10 mins, peak 20 mins, duration 1 - 4 hrs

IM
- onset 6-12 mins, peak unknown, duration 1- 4 hrs

IV
- onset rapid, peak 20 mins, duration 20 - 30 mins

17
Q

Benadryl Action

  • antagonizes the effects of histamine at the receptor site

Route
- SQ
- IM
- IV

A

SQ
- onset 15 - 60 mins, peak 2 - 4 hrs, duration 4 - 8 hrs

IM
- onset 20 - 30 mins, peak 2 - 4 hrs, duration 4 - 8 hrs

IV
- rapid onset, peak unknown, duration 4- 8 hrs

18
Q

Benadryl for Anaphylactic Reaction

PO: 25-50 mg every 4-6 hrs, not to exceed 300 mg/ day
IM, IV: 25-50 mg every 4 hrs, not to exceed 400 mg/ day

A

PO: 25-50 mg every 4-6 hrs, not to exceed 300 mg/ day
IM, IV: 25-50 mg every 4 hrs, not to exceed 400 mg/ day