Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Hematology > RBCs Overview, Origin, Regulation, + Morphology > Flashcards

RBCs Overview, Origin, Regulation, + Morphology Flashcards

1
Q

Who is she?
> 9um
Well hemoglobinized (lacks a central pallor)
Round Macrocytes - Liver disease
Oval Macrocytes - B12/folate deficiency, pernicious anemia

A

Macrocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Who Is She?

<6um
Central pallor due to decreased hemoglobin concentrations
Iron deficiency, Thalassemia, Sideroblastic (lead poisoning)

A

Microcyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Anisocytosis

A 
Any significant variation in size of RBC
Found in most anemias/leukemias
Often due to deficiency in raw material
Graded 1+ to 4+
Variation corresponds with RDW
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

RDW

A

Red blood cell Distribution Width
Variation in RBC size
Calculated from MCV and RBC
Indicator of degree pf anisocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Poikilocytosis

A

RBC variation in shape

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What percentage of blood is formed elements?

A

45%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the lifespan of the red blood cell and why

A

120 days, they don’t contain a nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which statement describes the role of RBCs in the body?

All of these describe RBCs
Flexible container for hemoglobin
Acts as a buffer for the pH of blood
Oxygen transporter

A

All of these describe RBCs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which glycoprotein hormone triggers the production of RBCs?

A

Erythropoietin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which of the following may cause elevated EPO?

Adrenal gland tumor
Smoking
High altitude

A

All the above

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which of the following can lead to a decreased level of EPO?

Renal failure
Thyroiditis
High altitude
Heart disease

A

Renal failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Where in the body does erythropoiesis typically occur in adults?

A

Bone marrow of long, flat bones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which cells “nurse” erythrocyte development?

A

Macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How can reticulocytes be differentiated from mature RBCs microscopically?

A

They tend to be larger, bluer and can appear to have a mesh-like appearance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What does hematocrit measure?

A

The percentage of blood composed of erythrocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Anemia with low reticulocyte count may indicate which of the following:

Chronic disease
Nutritional deficiencies
Renal failure

A

All the above

17
Q

A reticulocyte index is useful to determine:

A

if the patient’s bone marrow is responding to their anemia

18
Q

When may reticulocytosis occur?

Nutritional deficiencies
Aplastic anemia
Marrow failure
Post hemorrhage

A

Post hemorrhage

19
Q

What happens to RBCs at the end of their life span?

A

They are removed by macrophages and components recycled or eliminated

20
Q

What purpose does the peripheral smear serve?

A

To determine if cells appear normal

21
Q

What are the conditions associated with macrocytosis?

A

Pernicious anemia

Liver disease

22
Q

What is the term for significant variation in the size of a RBC population?

A

Anisocytosis

23
Q

Which of the following is associated with increased Red Blood Cell DIstribution Width (RDW)?

Nutritional deficiencies
Dehydration
Renal disease

A

Nutritional deficiencies

24
Q

Poikilocytosis is the term that refers to

A

RBCs of different shapes

25
Q

Which of the following tests may be useful in better understanding the finding of target cells?

Iron studies
Liver function tests
CBC with differential

A

All the above

26
Q

Which of the following can lead to schistocytes?

Dehydration
Sickle cell disease
RBC trauma from fibrin strands
IDA

A

RBC trauma from fibrin strands

27
Q

(T or F) Spherocytes are always associated with inheritance.

A

False

28
Q

Echinocytes are associated with

A

Uremia

29
Q

Which of the following conditions are associated with acanthocytes?

IDA
Alcoholic cirrhosis
B12 deficiency

A

Alcoholic cirrhosis

30
Q

Which of the following conditions are associated with elliptocytes?

Iron deficiency
Thalassemia
Genetics

A

All the above

31
Q

(T or F) The visualization of a dacrocyte is a medical emergency.

A

False

32
Q

What causes RBCs to sickle?

A

Low oxygen states in genetically susceptible individuals

Variation in hemoglobin coding in DNA

33
Q

What are Howell Jolly Bodies made from?

A

DNA remnants in RBCs

34
Q

What are Heinz bodies?

A

Denatured, precipitated hemoglobin

35
Q

Basophilic stippling is:

Associated with lead poisoning

When the bone marrow produces more basophils then RBCs

When basophils transport oxygen

A

Associated with lead poisoning

Hematology (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions