Nutrition Flashcards

1
Q

What is the most common reason sited for lack of response to iron supplementation?

A

Patient adherence issues

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2
Q
Which symptom is NOT associated with iron deficiency:
Diarrhea
Fatigue
Decreased cognitive ability
Pagophagia
A

Diarrhea

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3
Q

(T or F) One form of pica, the urge to eat ice is associated with iron deficiency and resolves with correction of the deficiency.

A

True

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4
Q

In which ways is iron balance maintained in the body?

A

Epidermal cell sloughing
Blood loss through menstruation
GI absorption

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5
Q

Which form of iron is most readily absorbed?

A

Heme iron

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6
Q

Which foods can block iron absorption?

A

Milk

Green tea

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7
Q

(T or F) Iron is more readily absorbed on an empty stomach but can cause irritation.

A

True

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8
Q

New research is demonstrating improved methods for dosing iron to increase its absorption. According to the research, which dosing method is preferred?

Low doses many times a day
Moderate doses every other day
Dose to bowel tolerance
The maximum RDA every day

A

Moderate doses every other day

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8
Q

New research is demonstrating improved methods for dosing iron to increase its absorption. According to the research, which dosing method is preferred?

Low doses many times a day
Moderate doses every other day
Dose to bowel tolerance
The maximum RDA every day

A

Moderate doses every other day

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9
Q

Which of the test is the most sensitive for detecting early (uncomplicated) iron deficiency?

A

Ferritin

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10
Q

Which testing can be used to determine response to iron supplementation in an iron deficiency individual?

Reticulocyte index
Hemoglobin
Ferritin
Each of these can be helpful at different time intervals.

A

Each of these can be helpful at different time intervals.

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11
Q

Your patient has increase serum homocysteine and normal serum methylmalonic acid leading you to suspect she has:

A

Folate deficiency

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12
Q

(T or F) B12 deficiency can lead to folate deficiency.

A

True

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13
Q

________ is the most common cause of B12 deficiency

A

Pernicious anemia

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14
Q

At what B12 level is a methylmalonic acid assay recommended?

A

150-300 ng/L

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15
Q

In what way is the schilling test useful?

A

It provides information about the source of the B12 deficiency

16
Q

Which conditions affect the intestinal absorption of B12?

A

SIBO
IBD
Tapeworm infections

17
Q

What form must B12 leave the stomach in order to be absorbed?

A

R factor bound B12

18
Q

Which conditions or states negatively affect the oral phase of B12 absorption?

A

Sympathetic state

Sjogren’s syndrome

19
Q

What are sxs of B12 deficiency?

A

Macrocytic anemia
GI disturbances such as anorexia and diarrhea
Numbness and paresthesia in extremities

20
Q

(T or F) Folate deficiency leads to neurologic deficits.

21
Q

What conditions/populations are associated with increased risk of folate deficiency?

A

Pregnancy
Alcohol abuse
Malabsorption syndromes
Tropical sprue

22
Q

What is the suggested supplementation ratio of zinc to copper?

A

15mg zinc
to
1mg copper

23
Q

Which mineral is essential for mobilization of iron from both enterocytes and ferritin?

24
What impairs copper absorption?
High iron intake | High zinc intake
25
What dietary factors inhibit zinc absorption?
Phytates | High non-heme iron intake
26
X-linked sideroblastic anemia can be treated by high doses of _____.
B6
27
(T or F) Iron rich foods and ascorbic acid may be harmful to those with sickle cell anemia.
True
28
(T or F) Zinc should be avoided by those with sickle cell anemia
False
29
Reduction of hemolytic events associated with G6PD has been demonstrated with supplementation of:
Vitamin E | Selenium
30
What mineral competes with zinc absorption and may become depleted with long-term zinc supplementation?
Copper
31
Which foods may be harmful to to individuals with hemochromatosis due to their effect on the liver?
Alcohol | Raw oysters
32
What is the primary treatment for hemochromatosis?
Regular phlebotomy to remove excess iron
33
(T or F) Individuals homozygous for hemochromatosis have a shorted life expectancy unless they donate blood regularly
True
34
(T or F) Zinc supplementation may be harmful to those with hemochromatosis.
True
35
Which mineral competes with iron for transferrin binding and has been shown to be beneficial for those with hemochromatosis?
Chromium