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Hematology > Nutrition > Flashcards

Nutrition Flashcards

1
Q

What is the most common reason sited for lack of response to iron supplementation?

A

Patient adherence issues

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2
Q 
Which symptom is NOT associated with iron deficiency:
Diarrhea
Fatigue
Decreased cognitive ability
Pagophagia
A

Diarrhea

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3
Q

(T or F) One form of pica, the urge to eat ice is associated with iron deficiency and resolves with correction of the deficiency.

A

True

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4
Q

In which ways is iron balance maintained in the body?

A

Epidermal cell sloughing
Blood loss through menstruation
GI absorption

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5
Q

Which form of iron is most readily absorbed?

A

Heme iron

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6
Q

Which foods can block iron absorption?

A

Milk

Green tea

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7
Q

(T or F) Iron is more readily absorbed on an empty stomach but can cause irritation.

A

True

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8
Q

New research is demonstrating improved methods for dosing iron to increase its absorption. According to the research, which dosing method is preferred?

Low doses many times a day
Moderate doses every other day
Dose to bowel tolerance
The maximum RDA every day

A

Moderate doses every other day

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8
Q

New research is demonstrating improved methods for dosing iron to increase its absorption. According to the research, which dosing method is preferred?

Low doses many times a day
Moderate doses every other day
Dose to bowel tolerance
The maximum RDA every day

A

Moderate doses every other day

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9
Q

Which of the test is the most sensitive for detecting early (uncomplicated) iron deficiency?

A

Ferritin

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10
Q

Which testing can be used to determine response to iron supplementation in an iron deficiency individual?

Reticulocyte index
Hemoglobin
Ferritin
Each of these can be helpful at different time intervals.

A

Each of these can be helpful at different time intervals.

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11
Q

Your patient has increase serum homocysteine and normal serum methylmalonic acid leading you to suspect she has:

A

Folate deficiency

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12
Q

(T or F) B12 deficiency can lead to folate deficiency.

A

True

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13
Q

________ is the most common cause of B12 deficiency

A

Pernicious anemia

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14
Q

At what B12 level is a methylmalonic acid assay recommended?

A

150-300 ng/L

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15
Q

In what way is the schilling test useful?

A

It provides information about the source of the B12 deficiency

16
Q

Which conditions affect the intestinal absorption of B12?

A

SIBO
IBD
Tapeworm infections

17
Q

What form must B12 leave the stomach in order to be absorbed?

A

R factor bound B12

18
Q

Which conditions or states negatively affect the oral phase of B12 absorption?

A

Sympathetic state

Sjogren’s syndrome

19
Q

What are sxs of B12 deficiency?

A

Macrocytic anemia
GI disturbances such as anorexia and diarrhea
Numbness and paresthesia in extremities

20
Q

(T or F) Folate deficiency leads to neurologic deficits.

A

False

21
Q

What conditions/populations are associated with increased risk of folate deficiency?

A

Pregnancy
Alcohol abuse
Malabsorption syndromes
Tropical sprue

22
Q

What is the suggested supplementation ratio of zinc to copper?

A

15mg zinc
to
1mg copper

23
Q

Which mineral is essential for mobilization of iron from both enterocytes and ferritin?

A

Copper

24
Q

What impairs copper absorption?

A

High iron intake

High zinc intake

25
Q

What dietary factors inhibit zinc absorption?

A

Phytates

High non-heme iron intake

26
Q

X-linked sideroblastic anemia can be treated by high doses of _____.

A

B6

27
Q

(T or F) Iron rich foods and ascorbic acid may be harmful to those with sickle cell anemia.

A

True

28
Q

(T or F) Zinc should be avoided by those with sickle cell anemia

A

False

29
Q

Reduction of hemolytic events associated with G6PD has been demonstrated with supplementation of:

A

Vitamin E

Selenium

30
Q

What mineral competes with zinc absorption and may become depleted with long-term zinc supplementation?

A

Copper

31
Q

Which foods may be harmful to to individuals with hemochromatosis due to their effect on the liver?

A

Alcohol

Raw oysters

32
Q

What is the primary treatment for hemochromatosis?

A

Regular phlebotomy to remove excess iron

33
Q

(T or F) Individuals homozygous for hemochromatosis have a shorted life expectancy unless they donate blood regularly

A

True

34
Q

(T or F) Zinc supplementation may be harmful to those with hemochromatosis.

A

True

35
Q

Which mineral competes with iron for transferrin binding and has been shown to be beneficial for those with hemochromatosis?

A

Chromium

Hematology (9 decks)

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