RBC INCLUSION BODIES Flashcards
CONTENT, OTHER NAMES, DISEASE ASSOCIATION
made up of AGGREGATED RNA
BASOPHILIC STIPPLINGS
form of basophilic stippling observed when there is INCREASED POLYCHROMATOPHILIA
FINE STIPPLING
form of basophilic stippling which may be observed in PLUMBISM or other disorders with IMPAIRED Hb H SYNTHESIS, in MEGALOBLASTIC ANEMIA, and in other forms of severe anemia
COARSE STIPPLING
made up of ERYTHROCYTIC COLLECTIONS OF IRON
SIDEROTIC GRANULES
described as multiple DARK BLUE irregular granules in PRUSSIAN BLUE IRON STAINING
SIDEROTIC GRANULES
described as PALE BLUE clusters in WRIGHT STAINING
PAPPENHEIMER BODIES
stain used to exhibit SIDEROTIC GRANULES
IRON STAIN: PERLS’ REAGENT THROUGH PRUSSIAN BLUE RXN
stains used to exhibit PAPPENHEIMER BODIES
- NEW METHYLENE BLUE
- WRIGHT STAIN
“naa siyay NEW PEN para mag WRIGHT (write)”
frequently appears SINGLY in a cell (only one per cell), usually round, and <1 um in diameter, blue to purple in color
HOWELL-JOLLY BODIES
composed of REMNANTS OF NUCLEAR CHROMATIN (DNA)
HOWELL-JOLLY BODIES
made up of MITOTIC SPINDLE REMNANTS
CABOT RINGS
described as threadlike structures that appear as PURPLE-BLUE LOOPS (FIGURE OF 8 APPEARANCE)
CABOT RINGS
most of the time APPEAR ECCENTRICALLY along the INNER RBC MEMBRANE, large, round, blue to purple materials
HEINZ BODIES
made up of DENATURED AND PRECIPITATED HEMOGLOBIN
HEINZ BODIES
described as small, multiple, EVENLY DISTRIBUTED THROUGHOUT THE RED CELL, granular, greenish-blue bodies
Hb H INCLUSION BODIES
made up of precipitated Hb H
Hb H INCLUSION BODIES
DISEASE ASSOC:
associated with LEAD POISONING, PYRIMIDINE-5’-NUCLEOTIDASE DEFICIENCY, THALASSEMIA, MEGALOBLASTIC ANEMIA, ALCOHOLISM, REFRACTORY ANEMIA
BASOPHILIC STIPPLING
DISEASE ASSOC:
associated with SIDEROBLASTIC ANEMIA, THALASSEMIA, HEMOCHROMATOSIS or HEMOSIDEROSIS
SIDEROTIC GRANULES
DSE ASSOC:
associated with MEGALOBLASTIC ANEMIA, AFTER SPLENECTOMY, THALASSEMIA
HOWELL-JOLLY BODIES
DISEASE ASSOC:
associated with MEGALOBLASTIC ANEMIA, REFRACTORY ANEMIA, LEAD POISIONING
CABOT RINGS
DSE ASSOC:
associated with G6PD DEFICIENCY, DIHA, UNSTABLE Hb DSE
HEINZ BODIES
DISEASE ASSOC:
associated with Hb H DISEASE
Hb H INCLUSION BODIES
other name for BASOPHILIC STIPPLING
PUNCTATE BASOPHILIA
SIDEROTIC GRANULES are aka
PAPPENHEIMER BODIES
inclusions in MEGALOBLASTIC ANEMIA
only according to the table for inclusion bodies, not sa anemia descrip
- BASOPHILIC STIPPLING
- HOWELL-JOLLY BODIES
- CABOT RINGS
inclusions in THALASSEMIA
only according to the table for inclusion bodies, not sa dse descrip
- DACRYOCTE
- BASOPHILIC STIPPLING
- SIDEROTIC GRANULES/PAPPENHEIMER BODIES
- HOWELL-JOLLY BODIES
positive for FEULGEN REACTION
HOWELL-JOLLY BODIES
4 supravital stains to demonstrate HEINZ BODIES
- BRILLIANT CRESYL BLUE
- NEW METHYLENE BLUE
- METHYL VIOLET
- CRYSTAL VIOLET
what is the appearance of RBCs with Hb H Bodies?
PITTED GOLF BALL
BASOPHILIC STIPPLING is aka
PUNCTATE BASOPHILIA
described as irregular, dark blue to purple granules EVENLY DISTRIBUTED within an RBC
BASOPHILIC STIPPLING