POIKILOCYTOSIS Flashcards

DESCRIPTION, OTHER NAMES, DISEASE ASSOCIATIONS

1
Q

amost spherical in shape; lacks the central pallor

A

SPHEROCYTE

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2
Q

elongated RBCs with a SLIT-LIKE CENTRAL PALLOR and may be considered as an artifact

A

STOMATOCYTE

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3
Q

RBCs with IRREGULARLY SPICULATED SURFACE

A

ACANTHOCYTE

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4
Q

RBCs with REGULARLY SPICULATED SURFACE

A

BURR CELL

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5
Q

oval-shaped RBCs

A

OVALOCYTE

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6
Q

elliptical (cigar-shaped) RBC

A

ELLIPTOCYTE

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7
Q

pear-shaped or TEARDROP-SHAPED RBCs

A

DACRYOCYTE

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8
Q

fragmented RBCs

A

SCHISTOCYTE

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9
Q

SICKLE- or crescent-shaped RBCs

A

DREPANOCYTE

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10
Q

RBCs which show a CENTRALLY STAINED AREA WITH A THIN OUTER RIM OF HEMOGLOBIN

A

TARGET CELL

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11
Q

HELMET-SHAPED schistocyte that may appear in MAHA

A

HELMET CELL

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12
Q

demonstrate a semicircular defect in their edge (resmbles a BITE MARK)

A

BITE CELL

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13
Q

FOLDED RBCs

A

BISCUIT CELL

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14
Q

BIPOLAR or CENTRAL DISTRIBUTION of hemoglobin

A

BRONZE ELLIPTOCYTE

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15
Q

as large as leukocytes; pale-pink staining ghost of the red cell membrane

A

SEMILUNAR BODY

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16
Q

other term for BITE CELL

A

DEGMACYTE

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17
Q

other terms for TARGET CELL

A
  1. LEPTOCYTE
  2. CODOCYTE
  3. PLATYCYTE
  4. GREEK HELMET CELL
  5. MEXICAN HAT CELL
  6. BULL’S EYE CELL
18
Q

other term for SCHISTOCYTE

A

SCHIZOCYTE

19
Q

other term for TEARDROP CELL

A

DACRYOCYTE

20
Q

other term for BURR CELL

A

ECHINOCYTE

21
Q

other terms for ACANTHOCYTE

A
  1. THORN CELL
  2. SPUR CELL
22
Q

other term for STOMATOCYTE

A

MOUTH CELL

23
Q

DSE ASSOC:

associated with ABETALIPOPROTEINEMIA, McLeod SYNDROME, PK DEFICIENCY

A

ACANTHOCYTE

24
Q

DISEASE ASSOC:

associated with UREMIA, PK DEFICIENCY

A

ECHINOCYTE (BURR CELL)

25
Q

DISEASE ASSOC:

associated with SOUTHEAST ASIAN OVALOCYTOSIS

A

OVALOCYTE

26
Q

DSE ASSOC:

associated with THALASSEMIA, HEREDITARY ELLIPTOCYTOSIS

A

ELLIPTOCYTE

27
Q

DISEASE ASSOC:

associated with PRIMARY MYELOFIBROSIS, MEGALOBLASTIC ANEMIA, THALASSEMIA

A

DACRYOCYTE

28
Q

DSE ASSOC:

associated with MAHA (TTP, HELLP, HUS, DIC), UREMIA

A

SCHISTOCYTE

29
Q

DSE ASSOC:

associated with SICKLE CELL ANEMIA, Hb SC DISEASE

A

DREPANOCYTE

30
Q

DISEASE ASSOC:

associated with THALASSEMIA, LCAT DEFICIENCY

A

TARGET CELL

31
Q

DISEASE ASSOC:

associated with HEREDITARY SPHEROCYTOSIS, AIHA, BURNS, ABO HDN

A

SPHEROCYTE

32
Q

DSE ASSOC:

associated with Rh DEFICIENCY SYNDROME, ELECTROLYTE IMBALANCE, DEHYDRATED HEREDITARY XEROCYTOSIS

A

STOMATOCYTE

BIG CLUE: “RHED TOMATO” - Sir Henry

33
Q

DSE ASSOC:

associated with G6PD DEFICIENCY

A

BITE CELL

34
Q

DSE ASSOC:

associated with Hb SC DISEASE

A

BISCUIT CELL

35
Q

DSE ASSOC:

associated with SICKLE CELL ANEMIA (aside from Drepanocyte)

A

BRONZE ELLIPTOCYTE

36
Q

DISEASE ASSOC:

associated with OVERT HEMOLYSIS

A

SEMILUNAR BODY

37
Q

ABETALIPOPROTEINEMIA is aka

A

BASSEN-KORNZWEIG SYNDROME

38
Q

MOST COMMON FORM OF STOMATOCYTOSIS

A

DEHYDRATED HEREDITARY STOMATOCYTOSIS

39
Q

characterized by DEFECTIVE APO B SYNTHESIS; VLDL, LDL, and CHYLOMICRON are NOT FOUND IN PLASMA

A

ABETALIPOPROTEINEMIA

40
Q

FORM OF DREPANOCYTE:

crescent-shaped with LONG PROJECTIONS; WHEN REOXYGENATED, THEY FRAGMENT!!!

A

IRREVERSIBLE SICKLE CELLS

41
Q

FORM OF DREPANOCYTE:

have LESS PRONOUNCED PROJECTIONS; WHEN REOXYGENATED, THEY RETURN TO THE ORGININAL!!!!

A

OAT-SHAPED CELLS