POIKILOCYTOSIS Flashcards
DESCRIPTION, OTHER NAMES, DISEASE ASSOCIATIONS
amost spherical in shape; lacks the central pallor
SPHEROCYTE
elongated RBCs with a SLIT-LIKE CENTRAL PALLOR and may be considered as an artifact
STOMATOCYTE
RBCs with IRREGULARLY SPICULATED SURFACE
ACANTHOCYTE
RBCs with REGULARLY SPICULATED SURFACE
BURR CELL
oval-shaped RBCs
OVALOCYTE
elliptical (cigar-shaped) RBC
ELLIPTOCYTE
pear-shaped or TEARDROP-SHAPED RBCs
DACRYOCYTE
fragmented RBCs
SCHISTOCYTE
SICKLE- or crescent-shaped RBCs
DREPANOCYTE
RBCs which show a CENTRALLY STAINED AREA WITH A THIN OUTER RIM OF HEMOGLOBIN
TARGET CELL
HELMET-SHAPED schistocyte that may appear in MAHA
HELMET CELL
demonstrate a semicircular defect in their edge (resmbles a BITE MARK)
BITE CELL
FOLDED RBCs
BISCUIT CELL
“BIPOLAR” or CENTRAL DISTRIBUTION of hemoglobin
BRONZE ELLIPTOCYTE
as large as leukocytes; pale-pink staining ghost of the red cell membrane
SEMILUNAR BODY
other term for BITE CELL
DEGMACYTE
other terms for TARGET CELL
- LEPTOCYTE
- CODOCYTE
- PLATYCYTE
- GREEK HELMET CELL
- MEXICAN HAT CELL
- BULL’S EYE CELL
other term for SCHISTOCYTE
SCHIZOCYTE
other term for TEARDROP CELL
DACRYOCYTE
other term for BURR CELL
ECHINOCYTE
other terms for ACANTHOCYTE
- THORN CELL
- SPUR CELL
other term for STOMATOCYTE
MOUTH CELL
DSE ASSOC:
associated with ABETALIPOPROTEINEMIA, McLeod SYNDROME, PK DEFICIENCY
ACANTHOCYTE
DISEASE ASSOC:
associated with UREMIA, PK DEFICIENCY
ECHINOCYTE (BURR CELL)
DISEASE ASSOC:
associated with SOUTHEAST ASIAN OVALOCYTOSIS
OVALOCYTE
DSE ASSOC:
associated with THALASSEMIA, HEREDITARY ELLIPTOCYTOSIS
ELLIPTOCYTE
DISEASE ASSOC:
associated with PRIMARY MYELOFIBROSIS, MEGALOBLASTIC ANEMIA, THALASSEMIA
DACRYOCYTE
DSE ASSOC:
associated with MAHA (TTP, HELLP, HUS, DIC), UREMIA
SCHISTOCYTE
DSE ASSOC:
associated with SICKLE CELL ANEMIA, Hb SC DISEASE
DREPANOCYTE
DISEASE ASSOC:
associated with THALASSEMIA, LCAT DEFICIENCY
TARGET CELL
DISEASE ASSOC:
associated with HEREDITARY SPHEROCYTOSIS, AIHA, BURNS, ABO HDN
SPHEROCYTE
DSE ASSOC:
associated with Rh DEFICIENCY SYNDROME, ELECTROLYTE IMBALANCE, DEHYDRATED HEREDITARY XEROCYTOSIS
STOMATOCYTE
BIG CLUE: “RHED TOMATO” - Sir Henry
DSE ASSOC:
associated with G6PD DEFICIENCY
BITE CELL
DSE ASSOC:
associated with Hb SC DISEASE
BISCUIT CELL
DSE ASSOC:
associated with SICKLE CELL ANEMIA (aside from Drepanocyte)
BRONZE ELLIPTOCYTE
DISEASE ASSOC:
associated with OVERT HEMOLYSIS
SEMILUNAR BODY
ABETALIPOPROTEINEMIA is aka
BASSEN-KORNZWEIG SYNDROME
MOST COMMON FORM OF STOMATOCYTOSIS
DEHYDRATED HEREDITARY STOMATOCYTOSIS
characterized by DEFECTIVE APO B SYNTHESIS; VLDL, LDL, and CHYLOMICRON are NOT FOUND IN PLASMA
ABETALIPOPROTEINEMIA
FORM OF DREPANOCYTE:
crescent-shaped with LONG PROJECTIONS; WHEN REOXYGENATED, THEY FRAGMENT!!!
IRREVERSIBLE SICKLE CELLS
FORM OF DREPANOCYTE:
have LESS PRONOUNCED PROJECTIONS; WHEN REOXYGENATED, THEY RETURN TO THE ORIGINAL!!!!
OAT-SHAPED CELLS