RBC Disroders

Question 1

HGB rule of three

Answer 1

HGBx3=hematocrit

-if the HMGx3 does not apply, they need to have the blood test repeated, it was an error

Question 2

How big a RBC

Answer 2

8 microns, the size of a lymphocyte nucleus

Question 3

How many more RBCs are there than WBCs

Answer 3

1000:1

Question 4

How many O2 molecules does one hemoglobin molecule carry?

Answer 4

4

Question 5

HGB and HCT are less than normal range

Answer 5

Anemia

Question 6

Hypochromic anemia

Answer 6

Low MCHC

-mean cell HGB concentration

Question 7

Hyperchromic anemia

Answer 7

High MCHC

-mean cell HGB concentration

Question 8

HGB<13.5

Answer 8

Anemia in men

Question 9

Hgb<12

Answer 9

Anemia in women

Question 10

Immature circulating RBCs

Answer 10

Reticulocytes

Question 11

Increased blood RBC mass

Answer 11

Polycythemia Vera

High HCT

Question 12

Microcytosis in MCV

Answer 12

<80

Question 13

Macrocytosis in MCV

Answer 13

> 100

Question 14

Normochromic anemia

Answer 14

32-36

Question 15

Hypochromic anemia

Answer 15

<32

Pale RBC

Question 16

Young RBC size

Answer 16

10 microns, larger than a mature one

Question 17

Causes of anemia

Answer 17

Blood loss
Impaired RBC production
Accelerated RBC desrtructgion

Question 18

Micorcytic anemia

Answer 18

Low MCV
Iron deficiency (MSOT COMMON IN THE WORLD)

Question 19

What is the most common microcytic anemia in the world

Answer 19

Iron deficiency

Question 20

What is iron deficiency a cause of

Answer 20

Chronic blood loss somewhere

Question 21

Macrocytic anemia is commonly what

Answer 21

B12 and folate deficiency

-child bearing women should take this

Question 22

If a women who does not have enough folate can have what happen to child

Answer 22

Neutrotube defect, spina bifida

Question 23

Low MCV and high RBC distribution (RDS)

Answer 23

Iron deficiency

-ferritin levels are the Dx step here

Question 24

MCV low, normal RDW (RBC distribution)

Answer 24

Thalassemia

Question 25

What’s the difference between iron deficiency and thalassemia

Answer 25

Normal ferritin: thalassemia

High ferritin: iron deficiency

Question 26

Loss of erythropoietin

Answer 26

Anemia of renal failure

Question 27

MCV large, Norma B12

Answer 27

Folate defeicnicy

Question 28

MCV >100, decreased B12

Answer 28

B12 defeicneicy

Question 29

Time to depletion of folate

Answer 29

3 months

Question 30

Time to depletion for B12 deficiency

Answer 30

3 years

Question 31

Between folate and B12, which one has more Neuro problems

Answer 31

B12

• essential for nerve conduction
• both of these can ultimately cause neuro problems in child

Question 32

What is needed to absorb B12

Answer 32

Intrinsic factor

Question 33

G6PF deficiency

Answer 33

Can protect against malaria

Question 34

What protects against malaria

Answer 34

Sickle cell anemia and G6PD

Question 35

Favism

Answer 35

X-linked, lysis triggered by consumption of favs beans

• protects from malaria
• G6PD defeicneicy

Question 36

Leading cause of anemia world wide

Answer 36

Iron deficiency anemia

Question 37

Dx of iron deficiency anemia

Answer 37

Microcytic, hypochromic anemia

Question 38

Two forms of thalassemia

Answer 38

alpha and beta

Question 39

Thalassemia: who is most likely to get it

Answer 39

Mediterranean

Question 40

asymptomatic, accidentally discovered, RBC count may be a little high, but they are very small (HGB, HCT)

Answer 40

Thalassemia

Question 41

Which anemia can have a normal to high RBC count

Answer 41

Thalassemia