RBC cases Flashcards

1
Q

hx: 6 yo F GSD HBC, lateral recumbency with thready pulses, <8 broken ribs, extremely painful

Laboratory Data: HCT: 26% (37-55)

RBC count: 3.88X10^12/L (5.5-8.5)

Hgb: 8.7 g/dl (12.0-18.0)

MCV: 66.8 (60.0-77.0

MCHC: 33.5 g/dl (31.0-34.0)

RBC morpho: WNL

Plasma color: N

TP: 3.2 g/dl (5.5-7.8(

albumin: 1.7 g/dl (2.8-4.0)

A

Moderate normocytic, normochromic non-regenerative anemia

likely internal bleeding into abdomen from the traumatic HBC

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2
Q

Hx: 9 yo mininature mare who presented for weakness, depression and colic, mm: pale & yellow, weak pulses and rapid swallow breathing, thin, poor BCS, anorexia, foaled several days ago, red/brown urine, no defecation in 2 days, normal gut sounds

HCT: 10% (30-51)

RBC count: 1.53 x 10^12/L (6.5-12.8)

Hgb: 3.6 g/dl (10.9-18.1)

MCV: 53.0 fl (35.0-53.0)

MCHC: 36.0 g/dl (34.6 38.0)

RBC morph: numerous Heinz bodies present, slightly increased anisocytosis

Plasma color: icteric, moderate hemolysis

TP: 7.0 g/dl (5.6-7.0)

albumin: 2.9 gdl (2.4-3.8)

A

severe normocytic, normochromic regenerative anemia

likely from intravascular hemolysis from a toxin such as red maple leave or onion/garlic

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3
Q

Hx: 6Y MN dog boarded last week, lethargic, vomiting

PE: Temp 101.8, Pulse: 130, Resp: 40/min, MM; pale/icteric, dull depressed, hydration-adequate, Sclera and gums-icteric

RBC: 2.8 (5.71-8.29)

Hgb: 7.83 (13.5-19.9)

HCT: 23.8 (38.5-56.7)

MCV: 85.1 (64.0-73.0)

MCHC: 32.9 (33.6-36.6)

RDW 18.7 (12.5-16.5)

TPP: 6.0 (5.8-7.2)

RBC morph: Anisocytosis +3, polychromasia 3+, spherocytes 3+, 13 nRBC

plasma color: icteric

A

Moderate macrocytic, hypochromic regenerative anemia

likely IMHA (spherocytes)

metarubricytosis

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4
Q

Hx: 9 yo Holstein-Friesian cow, calved 1 week ago, developed d 6 d ago, some other cows have d, given electrolyte therapy

PE: temp: 102, Pulse: 108 bpm, resp-68/min, MM: pink, hydration-~10% deh, QAR, BCS 3/5

RBC: 9.36 (5.52-8.48)

Hgb: 16.6 (8.6-13.6)

HCT: 44.6 (24.9-39.1)

MCV: 47.7 (39.2-52.2)

MCHC: 34.0 (33.5-35.7)

RDW: 21.0 (18.6-22.4)

TPP: 10.5 (6.9-9.4)

Alb: 4.3 (2.3-3.5)

RBC morph: normal

Plasma color: normal

A

Erythrocytosis with hyperproteinemia

likely due to dehydration from the diarrhea

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5
Q

Hx: 2.5 yo M GSD occasional v bile-tinged fluid, lethargy, & anorexia for few weeks

abdominocentesis-marked mixed inflammatory process

conc urine with mild pre-renal azotemia

leukocytosis with inflammatory profile

RBC: 4.48 (5.5-8.5)

Hgb: 10.4 (12-18)

HCT: 31 (37-55)

MCV: 71.2 (60-77)

MCHC: 33.5 (31-34)

TPP: 5.7 (5.2-7.2)

RBC morph: normal

Plasma: normal

A

mild normocytic, normochromic non regenerative anemia

Anemia of inflammatory disease

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6
Q

Hx: 6yo MN yellow lab, several weeks of intermittent diarrhea, occ melena

RBC: 3.2 (5.71-8.29)

Hgb: 5.89 (13.5-19.9)

HCT: 19 (39-57)

MCV: 60 (64-73)

MCHC: 31 (33.6-36.6)

TPP: 3.8 (5.2-7.2)

Reticulocytes: 24,900 (<80,000 ul)

rbc morph: 2+ keratocytes, 1+ schistocytes, 2+ hypochromasia

plasma: normal

A

Severe microcytic, hypochromic non-regenerative anemia

Schistocytes: DIC, vasculitis, vascular tumor

blood loss–>Fe defiency

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7
Q

Hx: 7 yo MN mixed breed dog presented for lethargy and vomiting

RBC: 1.47 (5.6-8)

Hgb: 3.4 (14-19)

HCT: 11 (40-55)

MCV: 77 (65-75)

MCHC: 30.1 (33-36)

TPP: 7.2 (6-8)

reticulocytes: 175,000 (<80,000 ul)

RBC morph: 3+ spherocytes, 2+ polychromasia, 2+ anisocytosis,

Plasma: mildly hemolyzed

A

Severe macrocytic, hypochromic regenerative anemia

likely due to IMHA

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8
Q

13 yo DSH presented for lethargy, partial anorexia for past month

RBC: 4.99 (7-10.5)

Hgb: 7.7 (10-16)

HCT: 24 (30-50)

MCV: 48.1 (42-53)

MCHC: 32.1 (30-33.5)

TPP: 7.9 (6.8-8.3)

Reticulocytes: 15,800 (<60,000 ul)

RBC morph: ~5% heinz body

plasma: normal

A

mild normocytic, normochromic non regenerative anemia

likely due to anemia of inflammation poss neoplasia

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9
Q

Hx: 6 mo, M Standard poodle, 1 week hx of anemia, lethargy, wt loss, large fluctuant submandibular swelling developed overnight

RBC: 2.56 (5.71-8.29)

Hgb: 5.7 (13.9–19.9)

HCT: 17 (38-56)

MCV: 83 (64-73)

MCHC: 32 (33.6-36.6)

TPP: 5.0 (5.8-7.6)

Reticulocytes: 153,000 (<80,000 ul)

RBC morph: 2+ polychromasia, 2+ anisocytosis

plasma: normal

A

Severe macrocytic, hypochromic regenerative anemia

hematoma in submandibular swelling

blood loss

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10
Q

hx: 4 yo Warmblood gelding, poor performance

HCT: 73 (27-43)

MCV: 48 (38-52)

MCHC: 35.8 (34.6-38.2)

TPP: 8.3 (4.6-11.6)

RBC morph: 2+ echinocyte

plasma: normal

A

erythrocytosis likely due to splenic contraction due to epinephrine

echinocytes likely to due slight dehydration after exercise

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11
Q

6 yo FS mixed breed dog with hx of CKD presented with increasing lethargy

RBC: 2.34 (5.5-8.5)

Hgb: 5.25 (12-18)

HCT: 15 (38-56)

MCV: 64 (60-72)

MCHC: 35 (34-38)

TPP: 6.4 (6-8)

Reticulocytes: 2,000 (<80,000/ul)

RBC morph: rare polychromasia

plasma normal

A

Severe normocytic, normochromic non-regenerative anemia

due to decrease Epo production and usually correlates with the severity of the CKD

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