RBC anomalies Flashcards
refers to erythrocytes with normal
amount of hemoglobin.
normochromic cell
refers to erythrocytes wherein the
central light area of the cell is larger and paler than the
normal
hypochromic cell
red cells which have an increased
hb content and wherein the central light area is
smaller than the normal
hyperchromic
his condition wherein the red cell are stained with
various shades of blue with tinges of pink.
Polychromatophilia or Polychromasia or Diffuse
Basophilia
Condition where in the
red cells appear pale
hypochromasia
2 possible causes of hypochromasia
Dec hb concentration
* Abnormal thinness of the
cells:
* IDA
* Sideroblastic anemia
* thalassemia
Conditioned wherein the
red cell are deeply
stained to abnormal
thickness of cells.
hyperchromasia
condition where in the red
cells vary in size both macrocytes and
microcytes coexist on the same smear.
Anisocytosis
larger than normal greater than
8 um in size round in shape mcv > 100 FL
Macrocyte
cell which is less than 6 um in size
MCV less than 80 fl
Microcyte
Abnormal cytoplasmic maturation but normal
nuclear maturation
defect of microcyte
large oval-shaped red cell which is 9-12
um
megalocyte
Abnormal nuclear maturation but normal
cytoplasmic maturation
defect of megalocyte
red cells exhibit variation in shape
Poikilocytosis
normal cell with a biconcave disc
shape with increased surface volume surface
discocyte
small dense
RBC with few irregularly
spaced projections of varying
length
acanthocyte
- Cell membrane is
folded - Cell assumes a “
Pocket book roll”
appearance or biscuit
shape
BISCUIT CELL ( FOLDED RBC)
cell with irregularly
spaced blunt processes,
resembles crenated RBC
burr cell or echinocyte
cell w/ eccentric
vacuoles due to the
plucked out Heinz body
blister cell or bite cell
ATP deficiency
due to prolonged
storage of
anticoagulated blood
- sea urchin cell
ECHINOCYTES OR CRENATED CELLS
Target cell/ Mexican Hat
/cells with bull’s eye
appearance
CODOCYTES
Def. in cholesterol,
phospholipid in the membrane
Def in Lecithin cholesterol acyl
transferase ( LCAT)
CODOCYTES
- abnormal
maturation squeezing
and fragmentation
during splenic passage - Cells appear in the
shape of a pear with a single short
or long protrusion.
TEARDROP CELL (DACRYOCYTE)
- Hb appears to be
concentrated at the two
ends of the cell leaving a
normal central area of pallor - can be found in healthy person
ELLIPTOCYTES or ovalo cyte