RBC and WBC Abnormalities

Question 1

General term for abnormally shaped RBCs?

Answer 1

Poikilocytosis

Question 2

General term for size abnormalities?

Answer 2

Anisocytosis

Question 3

Sphereocytes are indicative of what pathology?

Answer 3

Hereditary spherocytosis

Question 4

Would the MCHC be elevated or decreased in hereditary spherocytosis?

Answer 4

Elevated MCHC

Question 5

If the RBCs have a schistocyte appearance what pathology is indicated?

Answer 5

Traumatic hemolytic anemia

Question 6

A bite cell is caused by what?

Answer 6

A macrophage biting off a piece of abnormal RBCs

Question 7

Which anemia causes bite cell formation?

Answer 7

G6PD anemia

Question 8

Tear drop cells indicate what type of diseases?

Answer 8

Myeloproliferative diseases (ie. leukemias)

Question 9

What causes a rouleaux to form?

Answer 9

Inflammation (specifically fibrinogen release)

Question 10

A codocyte or target cell is indicative of which disease?

Answer 10

Thalassemia

Question 11

Thalassemia has Hypochromic, microcytic cells T or F?

Answer 11

True

Question 12

When band neutrophils are at 10% or greater what does this indicate?

Answer 12

An acute infection likely bacterial

Question 13

Hyper-segmented neutrophils have 6 or more lobes and indicate a deficiency of what?

Answer 13

Deficiency of B12/Folate

Question 14

Hyper-segmented neutrophils are often accompanied by what RBC change?

Answer 14

Macrocytic RBC